15 cases of large venous malformations in oral and maxillofacial region involving in multiple anatomical sites were treated by suture ligation and injection of pingyangmycin oleum iodisatum emulsion(PLE) for 2-5 times.Treatment effect of grade Ⅳ was observed in 12 cases,grade Ⅲ in 3 cases.No severe systemic adverse reaction and no local adverse reation were obseved in all cases.Suture ligation and PLE injection can enhance the therapeutic effect and reduce the adverse reactions in the treatment of large venous malformations of the oral and maxillofacial region.%采用缝扎注射PLE治疗口腔颌面部累及多个解剖部位的大型静脉畸形15例,并记录治疗次数、临床疗效及不良反应.15例患者经过2～5次治疗,疗效Ⅳ级12例,Ⅲ级3例;全部病例均未出现严重全身不良反应和局部组织坏死及功能障碍症状.缝扎注射PLE治疗口腔颌面部大型静脉畸形,可增强治疗效果,降低不良反应.
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