目的:探讨Er∶YAG激光和半导体激光双波长激光在牙周基础治疗中的疗效.方法:选取30例慢性牙周炎患者,随机分为3组(n=10)分别接受机械(scaling and root planning,SRP)、单纯Er∶YAG激光治疗(Er∶YAG laser therapy,ERT)、半导体+ Er∶YAG+半导体激光(twinlight laser therapy,TPT)治疗,治疗中记录患者疼痛VAS,治疗前后检测探诊深度(PD)、探诊出血指数(BOP)、临床牙周附着水平(CAL)、龈沟液中IL-1β、TNF-α、TGF-β及b-FGF含量、龈下菌斑中牙龈卟啉单胞菌(Pg)的相对数量.应用SPSS 21.0软件对数据进行统计分析.结果:在治疗后6周和12周时,TPT组指标PD、BOP、CAL、IL-1β和TNF-α含量、Pg相对总菌的含量的值均低于ERT和SRP组(P＜0.05),TPT组TGF-β及b-FGF含量均显著高于ERT、SRP组,双波长激光组的VAS值明显低于手工器械组(P＜0.05).结论:双波长激光具有很好的临床疗效,可促进牙周再附着.%Objective:To observe the effects of Er ∶YAG(erbium:yttrium-aluminum-garnet) laser combined with diode laser in the treatment of chronic periodontitis.Methods:30 patients with chronic periodontitis patients were treated by mechanical scaling and root planning(SRP),pure Er ∶ YAG laser(ERT),diode + Er ∶ YAG + diode laser therapy(TPT) respectively.In the treatment VAS pain score was recorded.Probing deepth (PD),clinical attachment level (CAL) and bleeding on probing (BOP) were examined,IL-1 β,TNF-α and b-FGF in GCF,Porphyromonas gingivalis(Pg) in subgingiva plaqure were measured before and after treatment.Data were analyzed by SPSS 21.0 software.Results:6 weeks,12 weeks after treatment PD,BOP and CAL in TPT group were lower than those in ERT and SRP groups(P ＜0.05),TGF-β and b-FGF in TPT group were higher,IL-1β and TNF-α were lower than those in ERT and SRP groups (P ＜ 0.05).The content of Pg relative to total bacteria in TPT group were lower than that in ERT and SRP groups (P ＜ 0.05),VAS value in twinlight laser group was significantly lower than hand instruments group(P ＜ 0.05).Conclusion:The twinlight laser is effective in the treatment of periodontitis.
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