目的 分析辛夷鼻炎丸与布地奈德联合治疗变应性鼻炎的临床效果.方法 选取我院收治的112例变应性鼻炎患者, 随机法分成对照组和观察组, 各56例.对照组应用布地奈德治疗, 观察组在此基础上加用辛夷鼻炎丸治疗, 比较两组临床疗效、患者血清IgE水平、LTE4含量及用药不良反应.结果 观察组总有效率为85.71％, 高于对照组的75.00％, 差异有统计学意义 (P＜0.05) ;治疗4周观察组患者血清LTE4含量、IgE水平均低于对照组, 差异有统计学意义 (P＜0.05) ;观察组不良反应发生率为5.36％, 低于对照组的12.50％, 但差异无统计学意义 (P＞0.05) .结论 辛夷鼻炎丸与布地奈德联合治疗变应性鼻炎的临床效果显著, 可改善患者血清IgE水平、LTE4含量, 安全性较好.%Objective To analyze the clinical effect of Xinyi Biyan Wan combined with budesonide in the treatment of allergic rhinitis. Methods 112 patients with allergic rhinitis admitted to our hospital were randomly divided into control group and observation group, 56 cases each. The control group was treated with budesonide. The observation group was treated with Xinyi Biyan Wan. The clinical efficacy, serum IgE level, LTE4 content and adverse drug reactions were compared between the two groups.Results The total effective rate of the observation group was 85.71％, which was higher than that of the control group 75.00％, the difference was statistically significant (P＜0.05) .In the 4 weeks of treatment, the serum LTE4 content and IgE level of the observation group were lower than those of the control group, the difference was statistically significant (P＜0.05) . The incidence of adverse reactions in the observation group was 5.36％, which was lower than that in the control group (12.50％) , but the difference was not statistically significant (P＞0.05) .Conclusion The clinical effect of Xinyi Biyan Wan combined with budesonide in the treatment of allergic rhinitis is significant, which can improve the serum IgE level and LTE4 content, and the safety is better.
展开▼
