目的：探讨脐动脉血流频谱变化监测应用于胎儿宫内生长迟缓的诊断价值。方法：选取2011年2月1日-2014年2月1日在本院接受治疗的52例胎儿宫内生长迟缓患者作为观察组，选择同期在本院分娩的52例正常妊娠妇女作为对照组，两组均接受彩色多普勒监测，对比两组的监测结果。结果：随着孕周的不断增加，两组脐动脉舒张末期峰值血流速度、时间平均血流速度、收缩期峰值血流速度呈现不断上升的趋势，但观察组舒张末期峰值血流速度低于对照组。两组阻力指数、搏动指数、收缩与舒张之比呈现不断下降的趋势，但观察组的阻力指数、搏动指数、收缩与舒张之比高于对照组，差异有统计学意义（P<0.05）。胎儿宫内生长迟缓患者中，治疗无效1例，有效9例，显效42例，观察组的有效率达到98.08%。对照组满意度高达96.15%，观察组高达98.08%。两组满意度比较差异无统计学意义（P>0.05）。结论：早期监测脐动脉血流频谱变化，有利于及早发现脐动脉血流频谱异常，为临床治疗提供可靠的治疗依据。%Objective:To focus on exploring the value of monitoring the changes of umbilical artery blood flow spectrum for diagnosis of intrauterine growth retardation.Method:52 patients with intrauterine growth retardation who received treatment in our hospital from February 1st,2011 to February 1st, 2014 were chosen as the observation group.At the same time, 52 pregnant women with normal pregnancy were chosen as the control group.The two groups of pregnant women were under the monitoring of color Doppler.The monitoring results of the two groups were compared at last. Result:As the gestational weeks increased, the end diastolic velocity EDV), peak diastolic velocity (PDV), mean flow velocity(MFV) and peak systolic velocity (PSV) of umbilical artery of the two groups showed rising trend.However, the EDV and PDV of the observation group were much lower than that of control group.The resistance index(RI),pulsatility index (PI) and ratio of systolic and diastolic(S/D ratio) of the two groups showed a decreasing trend.The RI,PI and S/D ratio of the observation group were still higher than that of the control group.Changes of umbilical artery hemodynamics of pregnant women in the two groups were significantly different(P<0.05).Conclusion:The early monitoring of changes of umbilical artery blood flow spectrum is helpful to discover the abnormity of umbilical artery blood flow spectrum, which provides reliable basis for the clinical treatment.
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