首页> 中文期刊> 《中国医学创新》 >妊娠期肝内胆汁淤积症总胆汁酸水平及终止妊娠时间与围产儿结局的关系

妊娠期肝内胆汁淤积症总胆汁酸水平及终止妊娠时间与围产儿结局的关系

         

摘要

目的:探究妊娠期肝内胆汁淤积症 (intrahepatic cholestasis of pregnancy, ICP) 总胆汁酸 (total bile acid, TBA) 水平及终止妊娠的不同时间对围产儿结局产生的影响.方法:选取本院2017年1月-2018年6月住院分娩的妊娠期肝内胆汁淤积症孕妇60例作为研究对象, 根据其体内总胆汁酸水平进行分组, 将总胆汁酸水平40 mol/L且孕周<36周时, 终止产妇妊娠可以降低围产儿发生不良结局的发生率, 控制总胆汁酸水平相关指标的平衡, 采取积极治疗的方式可治疗妊娠期肝内胆汁淤积症孕妇.%Objective:To explore the effect of total bile acid (TBA) level and different termination time of pregnancy in intrahepatic cholestasis of pregnancy (ICP) and its influence on perinatal outcome.Method:A total of 60 pregnant women with intrahepatic cholestasis of pregnancy who were hospitalized and delivered in our hospital from January 2017 to June 2018 were selected as the study objects.According to their total bile acid levels, 30 cases pregnant women with total bile acid levels<40 mol/L were divided into low level group (group A), including 10 cases pregnant women with termination of gestational weeks<36 weeks as AC group and20 cases pregnant women with termination of gestational weeks≥36 weeks as AD group;30 cases pregnant women with total bile acid levels≥40 mol/L were divided into high level group (group B), including 9cases pregnant women with termination of gestational weeks<36 weeks as BC group and 21 cases pregnant

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