ObjectiveTo investigate the effect of intrapartum analgesia at different stages on maternal-infant outcome.MethodsA total of 108 cases of puerperae voluntarily accepted intrapartum analgesia were divided into observation group(58 cases)and control group(50 cases)according to different stages of analgesia. Puerperae in the observation group were performed intrapartum analgesia in the incubation stage(uterus cervix diameter less than 3cm),while puerperae in the control group were performed intrapartum analgesia in the active stage(uterus cervix diameter no less than 3cm). The maternal-infant outcomes of puerperae in the two groups were compared.ResultsThe analgesic effects in puerperae in the observation group when uterus cervix was 3cm and 5cm were significantly better than in the control group(P<0.01,P<0.05);the eutocia rate,cesarean section rate and vaginal instrumental delivery rate in the observation group were 44.12%,35.29% and 20.59%,while those in the control group were 46.67%, 33.33% and 20%,and the difference in delivery modes of puerperae in the two groups was not statistically significant(P>0.05);the incubation stage of first stage of labor in the observation group was significantly shorter than in the control group(P<0.01),and the differences in the active stage of first stage of labor,second stage of labor or third stage of labor between the two groups were not statistically significant(P>0.05);The postpartum lactation time in the observation group was significantly advanced than in the control group(P<0.05);the differences in amount of postpartum bleeding,amniotic fluid pollution rate,Apgar score of newborns at 1min and neonatal mortality rate were not statistically significant(P>0.05);the adverse effects rates of puerperae in the two groups during delivery process were respectively 27.94% and 26.67%,and the difference between the two groups was not statistically significant(P>0.05).ConclusionPerforming intrapartum analgesia on puerperae in incubation stage can enhance analgesic effect and shorten stages of labor and time of lactation,and won’t add the adverse effects of puerperae during delivery process. The overall effect of this therapy is better than intrapartum analgesia in active stage.%目的：探讨不同时机分娩镇痛对产妇母婴结局的影响。方法自愿接受分娩镇痛的产妇108例，按实施分娩镇痛的不同时机分为观察组58例与对照组50例，观察组产妇在潜伏期（宫颈口直径<3cm）实施分娩镇痛，对照组产妇在活跃期（宫颈口直径≥3cm）实施分娩镇痛，比较两组产妇的母婴结局情况。结果观察组产妇在宫口开至3cm、5cm时镇痛效果均明显优于对照组（P<0.01，P<0.05）；观察组及对照组顺产率、剖宫产率及阴道助产率分别为44.12%、35.29%、20.59%和46.67%、33.33%、20.0%，两组分娩方式比较差异无统计学意义（P>0.05）；观察组第一产程潜伏期显著较对照组缩短（P<0.01），第一产程活跃期、第二产程及第三产程与对照组比较，差异均无统计学意义（P>0.05）；观察组产后开始泌乳时间明显比对照组提前（P<0.05），两组产后出血量、羊水污染率、新生儿1分钟Apgar评分及新生儿病死率比较差异均无统计学意义（P>0.05）；两组产妇分娩过程中不良反应发生率分别为27.94%、26.67%，两组比较差异无统计学意义（P>0.05）。结论潜伏期对产妇进行分娩镇痛可提高镇痛效果，缩短产程，缩短开始泌乳时间，且未增加产妇分娩期间的不良反应，整体效果优于活跃期分娩镇痛。
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