Objective To analyze the causes of misdiagnosis of Primary sjogren's syndrome(PSS),so as to improve the diagnosis of PSS. Methods The clinical data of 120 patients with PSS misdiagnosed from January 2012 to January 2017 were analyzed retrospectively.Results The misdiagnosis rate in this research was 51.67%. 12 cases were misdiagnosed as Rheumatoid Arthritis,8 cases as thrombocytopenia,7 cases as anemia, 6 cases as leucopenia,5 cases as interstitial lung disease,and 4 cases raynaud dsease,hypokalemic paralysis,aged xerostomia respectively, and 3 cases lymphadenitis,fatigue syndrome,and 2cases abdominal pain,erythema nodosum,1 case as veinous thrombosis,conjunctivitis. ConclusionPSS is complicated and easy to misdiagnose. Detailed history and regular physical examination,and reasonable application of various auxiliary examination methods should be involved in order to reduce the misdiagnosis.%目的 分析原发性干燥综合征(PSS)误诊为其他疾病的原因,以提高本病诊断的准确率.方法 回顾性分析2012年1月至2017年1月120例PSS误诊患者的临床资料.结果 本组误诊率为51.67%.误诊为类风湿关节炎12例,血小板减少症8例,贫血7例,白细胞减少症6例,间质性肺病5例,雷诺征、低钾性麻痹及老年性口干各4例,淋巴结炎及疲劳综合症各3例,腹痛及结节性红斑各2例,静脉血栓及结膜炎各1例.结论 PSS的临床表现复杂多样,容易误诊,临床医师应积累临床经验,及时询问病史并作相关检查,以早期诊断,减少误诊.
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