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Efficacy of the oral neurokinin-1 receptor antagonist aprepitant administered with ondansetron for the prevention of postoperative nausea and vomiting

机译：恩丹西酮口服神经激肽-1受体拮抗剂阿瑞吡坦预防术后恶心和呕吐的功效

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摘要

Background5-HT3 receptor antagonist, dexamethasone and droperidol were used for the prevention of postoperative nausea and vomiting (PONV). Recently, neurokinin-1 (NK1) antagonist has been used for PONV. We evaluated the effect of oral aprepitant premedication in addition to ondansetron.

机译：Background5-HT3受体拮抗剂，地塞米松和氟哌利多用于预防术后恶心和呕吐（PONV）。最近，神经激肽-1（NK1）拮抗剂已用于PONV。除恩丹西酮外，我们还评估了口服阿瑞匹坦预防性用药的效果。

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期刊名称 Korean Journal of Anesthesiology
作者
Chae Seong Lim; Young-Kwon Ko; Yoon-Hee Kim; Sang-Il Park; Jae-Kook Kim; Myoung-Joong Kim; Hyun-Joong Kim;
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作者单位

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年(卷),期 2013(64),3
年度 2013
页码 212–217
总页数 6
原文格式 PDF
正文语种
中图分类麻醉学;麻醉学;
关键词
Aprepitant Ondansetron PONV;

机译：阿瑞吡坦;恩丹西酮;PONV;

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专利

1. Phase II study to evaluate the safety and efficacy of the oral neurokinin-1 receptor antagonist casopitant (GW679769) administered with ondansetron for the prevention of postoperative and postdischarge nausea and vomiting in high-risk patients. [J] . Singla NK, Singla SK, Chung F, Anesthesiology . 2010,第1期

机译：II期研究评估了恩丹西酮与口服神经激肽-1受体拮抗剂casopitant（GW679769）的安全性和有效性，以预防高危患者的术后和出院后恶心和呕吐。
2. The oral neurokinin-1 antagonist aprepitant for the prevention of chemotherapy-induced nausea and vomiting: a multinational, randomized, double-blind, placebo-controlled trial in patients receiving high-dose cisplatin--the Aprepitant Protocol 052 Stu [J] . Hesketh PJ, Grunberg SM, Gralla RJ, Journal of Clinical Oncology . 2003,第22期

机译：口服神经激肽1拮抗剂aprepitant预防化疗引起的恶心和呕吐：一项多国，随机，双盲，安慰剂对照试验，用于接受大剂量顺铂治疗的患者-Aprepitant协议052 Stu
3. Comparing the efficacy of aprepitant and ondansetron for the prevention of postoperative nausea and vomiting (PONV): A double blinded, randomised control trial in patients undergoing breast and thyroid surgeries [J] . Salome Jeyabalan, Suma Mary Thampi, Reka Karuppusami, Indian journal of Anaesthesia . 2019,第4期

机译：比较阿瑞匹坦和恩丹西酮在预防术后恶心和呕吐（PONV）方面的功效：一项在乳腺癌和甲状腺手术患者中进行的双盲，随机对照试验
4. EFFICACY OF ONDANSETRON CONTINUOUS INFUSION AND BOLUS INTRAVENOUS FOR POSTOPERATIVE NAUSEA AND VOMITING [C] . Rina Saputri, Abdul Rahem, Anita Purnamayanti Sari Mulia International Conference on Health and Sciences . 2018

机译：术术术后恶心和呕吐的ondansetron连续输注和推注的疗效
5. A Clinical Decision Tool to Guide Prevention of Adult Postoperative Nausea and Vomiting During Ondansetron Shortages [D] . Bernal, Diana Isabel. 2020

机译：导致预防成人术后恶心的临床决策工具，ondansetron短缺期间呕吐
6. Neurokinin-1 Receptor Antagonists in Preventing Postoperative Nausea and Vomiting [O] . Meng Liu, Hao Zhang, Bo-Xiang Du, -1

机译：Neurokinin-1受体拮抗剂在预防术后恶心和呕吐中的作用
7. Phase II Study to Evaluate the Safety and Efficacy of the Oral Neurokinin-1 Receptor Antagonist Casopitant (GW679769) Administered with Ondansetron for the Prevention of Postoperative and Postdischarge Nausea and Vomiting in High-risk Patients [O] . Neil K. Singla, Sonia K. Singla, Frances Chung, 2010

机译：II期研究以评估口腔内喹啉-1受体拮抗剂（GW679769）的安全性和疗效，用于预防术后和后收费恶心并在高危患者中呕吐

Efficacy of the oral neurokinin-1 receptor antagonist aprepitant administered with ondansetron for the prevention of postoperative nausea and vomiting

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