首页> 美国卫生研究院文献>Emerging Themes in Epidemiology >The validation of a three-stage screening methodology for detecting active convulsive epilepsy in population-based studies in health and demographic surveillance systems
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The validation of a three-stage screening methodology for detecting active convulsive epilepsy in population-based studies in health and demographic surveillance systems

机译:在健康和人口监测系统中基于人群的研究中检测活动性惊厥性癫痫的三阶段筛查方法的验证

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摘要

BackgroundThere are few studies on the epidemiology of epilepsy in large populations in Low and Middle Income Countries (LMIC). Most studies in these regions use two-stage population-based screening surveys, which are time-consuming and costly to implement in large populations required to generate accurate estimates. We examined the sensitivity and specificity of a three-stage cross-sectional screening methodology in detecting active convulsive epilepsy (ACE), which can be embedded within on-going census of demographic surveillance systems.We validated a three-stage cross-sectional screening methodology on a randomly selected sample of participants of a three-stage prevalence survey of epilepsy. Diagnosis of ACE by an experienced clinician was used as ‘gold standard’. We further compared the expenditure of this method with the standard two-stage methodology.
机译:背景技术在中低收入国家(LMIC)中,有关大批人群癫痫流行病学的研究很少。这些地区的大多数研究都使用基于人口的两阶段筛查调查,这种调查既耗时又成本高昂,需要大量人口才能生成准确的估算值。我们检查了三阶段横断面筛查方法在检测活动性惊厥性癫痫(ACE)中的敏感性和特异性,该方法可以嵌入正在进行的人口普查系统中。我们验证了三阶段横断面筛查方法对癫痫病的三阶段患病率调查参与者的随机选择样本。经验丰富的临床医生对ACE的诊断被用作“黄金标准”。我们进一步将该方法的支出与标准的两阶段方法进行了比较。

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