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An Overview of Dietary Interventions and Strategies to Optimize the Management of Non-Alcoholic Fatty Liver Disease

机译:饮食干预和优化非酒精性脂肪性肝病管理的策略概述

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摘要

>Aim: To investigate the efficacy of lifestyle adjustment strategies as a preventive measure and/or treatment of obesity-related non-alcoholic fatty liver disease in adults. >Method: A systematic review of literature through 1 July 2017 on the PubMed Database was performed. A comprehensive search was conducted using key terms, such as non-alcoholic fatty liver disease (NAFLD), combined with lifestyle intervention, diet, and exercise. All of the articles and studies obtained from the search were reviewed. Redundant literature was excluded. >Results: Several types of dietary compositions and exercise techniques were identified. Most studies concluded and recommended reduction in the intake of saturated and trans fatty acids, carbohydrates, and animal-based protein, and increased intake of polyunsaturated fatty acids (PUFAs), monounsaturated fatty acids (MUFAs), plant-based proteins, antioxidants, and other nutrients was recommended. The Mediterranean and Paleo diet both seem to be promising schemes for NAFLD patients to follow. Exercise was also encouraged, but the type of exercise did not affect its efficacy as a NAFLD treatment when the duration is consistent. >Conclusions: Although these different dietary strategies and exercise regimens can be adopted to treat NAFLD, current literature on the topic is limited in scope. Further research should be conducted to truly elucidate which lifestyle adjustments individually, and in combination, may facilitate patients with obesity-related NAFLD.
机译:>目标:研究生活方式调整策略作为成年人肥胖相关的非酒精性脂肪肝疾病的预防措施和/或治疗方法的功效。 >方法:对截至2017年7月1日在PubMed数据库上的文献进行了系统的综述。使用关键术语(例如非酒精性脂肪肝疾病(NAFLD))以及生活方式干预,饮食和运动进行了全面搜索。检索了所有从搜索中获得的文章和研究。多余的文献被排除在外。 >结果:确定了几种饮食组成和锻炼方法。大多数研究得出结论并建议减少饱和和反式脂肪酸,碳水化合物和动物性蛋白质的摄入,并增加多不饱和脂肪酸(PUFA),单不饱和脂肪酸(MUFA),植物性蛋白质,抗氧化剂和建议其他营养素。地中海饮食和古饮食都似乎是NAFLD患者遵循的有希望的方案。还鼓励进行锻炼,但是在持续时间一致的情况下,锻炼的类型不会影响其作为NAFLD治疗的疗效。 >结论:尽管可以采用这些不同的饮食策略和运动方案来治疗NAFLD,但有关该主题的当前文献范围有限。应该进行进一步的研究,以真正阐明哪种生活方式的单独调整或组合调整可以促进肥胖相关NAFLD患者的生活。

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