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Hospital Malnutrition and Inflammatory Response in Critically Ill Children and Adolescents Admitted to a Tertiary Intensive Care Unit

机译:进入重症监护病房的重症儿童和青少年的医院营养不良和炎症反应

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摘要

Critical illness has a major impact on the nutritional status of both children and adults. A retrospective study was conducted to evaluate the incidence of hospital malnutrition at a pediatric tertiary intensive care unit (PICU). Serum concentrations of IL-6 in subgroups of well-nourished and malnourished patients were also evaluated in an attempt to identify those with a potential nutritional risk.METHODSA total of 1077 patients were enrolled. Nutritional status was evaluated by Z-score (weight for age). We compared mortality, sepsis incidence, and length of hospital stay for nourished and malnourished patients. We had a subgroup of 15 patients with severe malnutrition (MN) and another with 14 well-nourished patients (WN). Cytokine IL-6 determinations were performed by enzyme-linked immunosorbent assay.
机译:严重疾病对儿童和成人的营养状况都有重大影响。进行了一项回顾性研究,以评估小儿三级重症监护病房(PICU)医院营养不良的发生率。还对营养丰富和营养不良患者亚组的血清IL-6浓度进行了评估,以试图确定具有潜在营养风险的患者.METHODSA共有1077名患者入组。营养状况通过Z评分(年龄体重)进行评估。我们比较了营养不良和营养不良患者的死亡率,败血症发生率和住院时间。我们有一个亚组,包括15名严重营养不良(MN)的患者和另一个14名营养丰富的患者(WN)的患者。通过酶联免疫吸附测定法测定细胞因子IL-6。

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