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The Role of Varicocele Repair in the New Era of Assisted Reproductive Technology

机译:精索静脉曲张修复在辅助生殖技术新时代中的作用

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摘要

Infertility affects 10–15% of couples who are trying to conceive, and half of the cases are due to male infertility. Intracytoplasmic sperm injection is increasingly being used to overcome multiple sperm deficiencies. Due to its effectiveness, some have proposed ICSI as a solution for all cases of male infertility, regardless of the cause. Hence, even men with potentially treatable causes of infertility have sought the aid of assisted reproductive technology, rather than undergo specific therapies to treat their infertility. Varicoceles are the most frequent physical finding in infertile men; indeed, they may be responsible for nearly one-third of cases of male infertility. Varicocele management, however, has always been a controversial issue because very few randomized, controlled studies have been performed to examine varicocelectomy as an infertility treatment. Significant evidence suggests that varicoceles have a harmful effect on the testis and that varicocelectomy can not only prevent progressive decline in testicular function but also reverse the damage. However, the degree to which varicocele repair improves pregnancy rates and the success of assisted reproductive technology remains controversial.
机译:不孕症影响了试图怀孕的夫妇的10%至15%,其中一半是男性不育所致。越来越多地使用胞浆内精子注射来克服多种精子缺陷。由于其有效性,有人提出将ICSI作为所有男性不育病例的解决方案,无论其原因如何。因此,即使有潜在的不育原因的男性也寻求辅助生殖技术的帮助,而不是接受治疗不育症的特定疗法。精索静脉曲张是不育男性中最常见的体征。确实,他们可能对男性不育症的近三分之一负责。然而,精索静脉曲张的治疗一直是一个有争议的问题,因为很少有随机,对照研究将精索静脉曲张切除术作为不育治疗方法进行检查。大量证据表明精索静脉曲张对睾丸有有害影响,精索静脉曲张切除术不仅可以防止睾丸功能的逐步下降,而且可以逆转损伤。然而,精索静脉曲张修复在多大程度上提高了妊娠率以及辅助生殖技术的成功仍存在争议。

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