首页> 美国卫生研究院文献>Molecular Cancer >SOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignancies

【2h】

SOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignancies

机译：SOX11表达与启动子甲基化相关并调节造血系统恶性肿瘤中的肿瘤生长

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

BackgroundThe transcription factor SOX11 plays an important role in embryonic development of the central nervous system (CNS) and is expressed in the adult immature neuron but is normally not expressed in any other adult tissue. It has recently been reported to be implicated in various malignant neoplasms, including several lymphoproliferative diseases, by its specific expression and in some cases correlation to prognosis. SOX11 has been shown to prevent gliomagenesis in vivo but the causes and consequences of aberrant expression of SOX11 outside the CNS remain unexplained.

机译：背景转录因子SOX11在中枢神经系统（CNS）的胚胎发育中起重要作用，并在成年未成熟神经元中表达，但通常在任何其他成年组织中均不表达。最近据报道，它的特异性表达以及与预后的相关性与多种恶性肿瘤有关，包括几种淋巴增生性疾病。已经显示出SOX11可以在体内预防神经胶质瘤的发生，但是尚无法解释中枢神经系统外SOX11异常表达的原因和后果。

著录项

期刊名称 Molecular Cancer
作者
Elin Gustavsson; Sandra Sernbo; Elin Andersson; Donal J Brennan; Michael Dictor; Mats Jerkeman; Carl AK Borrebaeck; Sara Ek;
展开▼
作者单位

展开▼
年(卷),期 2010(9),-1
年度 2010
页码 187
总页数 12
原文格式 PDF
正文语种
中图分类分子生物学;肿瘤学;
关键词

相似文献

外文文献
中文文献
专利

1. 肝癌细胞系中肝癌转移相关候选基因启动子区域CpG岛甲基化和表达水平的相关性研究 [J] . 李建良, 费琦, 余坚, 癌症（英文版） . 2004,第009期
2. SOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignancies [J] . Elin Gustavsson, Sandra Sernbo, Elin Andersson, Molecular Cancer . 2010,第2期

机译：SOX11表达与启动子甲基化相关，并调节造血系统恶性肿瘤中的肿瘤生长
3. Promoter methylation status of the tumor suppressor gene SOX11 is associated with cell growth and invasion in nasopharyngeal carcinoma [J] . Song Zhang, Shuo Li, Jin-Liang Gao Cancer Cell International . 2013,第1期

机译：抑癌基因SOX11的启动子甲基化状态与鼻咽癌的细胞生长和侵袭有关
4. Promoter methylation status of the tumor suppressor gene SOX11 is associated with cell growth and invasion in nasopharyngeal carcinoma [J] . Song Zhang, Shuo Li, Jin-Liang Gao Cancer Cell International . 2013,第1期

机译：抑癌基因SOX11的启动子甲基化状态与鼻咽癌的细胞生长和侵袭有关
5. OVEREXPRESSION OF ELFN2 IN GLIOMA REGULATED BY GENE PROMOTER HYPOMETHYLATION [C] . Liu Xiaoping, Yu Zhibin, Wang Zeyou, Progress on post-genome technologies and modern natural products . 2011

机译：基因启动子过甲基化调节胶质瘤中ELFN2的过表达
6. Progressive chromatin repression and promoter methylation of CTNNA1 associated with advanced myeloid malignancies. [D] . Ye, Ying. 2010

机译：CTNNA1的渐进性染色质抑制和启动子甲基化与晚期髓样恶性肿瘤相关。
7. Promoter methylation status of the tumor suppressor gene SOX11 is associated with cell growth and invasion in nasopharyngeal carcinoma [O] . Song Zhang, Shuo Li, Jin-Liang Gao 2013

机译：抑癌基因SOX11的启动子甲基化状态与鼻咽癌的细胞生长和侵袭有关
8. SOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignancies [O] . Brennan Donal J, Andersson Elin, Sernbo Sandra, 2010

机译：SOX11表达与启动子甲基化相关，并调节造血系统恶性肿瘤中的肿瘤生长
9. ERG Expression Levels in Prostate Tumors Reflect Functional Status of the Androgen Receptor (AR) as a Consequence of Fusion of ERG with AR Regulated Gene Promoters [R] . 2010

机译：前列腺肿瘤中ERG表达水平反映雄激素受体（aR）的功能状态，作为ERG与aR调节基因启动子融合的后果

SOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignancies

摘要

著录项

相似文献

相关主题

期刊订阅