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Is There any Relationship Between Extra-Pulmonary Manifestations of Mycoplasma Pneumoniae Infection and Atopy/Respiratory Allergy in Children?

机译:小儿肺炎支原体感染的肺外表现与儿童特应性/呼吸道过敏之间是否有关系?

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摘要

Mycoplasma pneumoniae is a common cause of respiratory infections in children, but sometimes extra-pulmonary diseases can be observed. The immunological mechanisms involved in these extra-respiratory complications are unknown. Here, we report a small case series of Mycoplasma-related diseases including 5 children who developed: i) aseptic meningitis; ii) urticarial rash and pericardial effusion; iii) pleural effusion with severe eosinophilia; iv) Stevens-Johnson syndrome; v) multiform erythema. Interestingly, all children were moderately to highly atopic, as a common immunologic feature.
机译:肺炎支原体是儿童呼吸道感染的常见病因,但有时可观察到肺外疾病。这些呼吸外并发症所涉及的免疫机制尚不清楚。在这里,我们报告了一系列与支原体相关的疾病的小病例,其中包括5名患儿:i)无菌性脑膜炎; ii)荨麻疹和心包积液; iii)胸腔积液伴严重嗜酸性粒细胞增多; iv)史蒂文斯-约翰逊综合症; v)多形性红斑。有趣的是,作为常见的免疫学特征,所有儿童均属于中度至高度特应性。

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