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Schizophrenia with obsessive compulsive features

机译:强迫症型精神分裂症

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摘要

While the obsessive compulsive (OC) phenomena in schizophrenia have been described over the years, the condition has received increasing attention in recent years. The clinical and biological significance of OC symptoms in schizophrenia, however, still remain controversial. Although OC symptoms in schizophrenia were once thought to occur rarely and were associated with more benign clinical courses, recent studies have shown greater prevalence rate and poor outcome. In addition, the OC subgroup of schizophrenia responds poorly to the traditional antipsychotic treatments, but may respond positively to adjunctive anti-OCD regimen according to the emerging clinical evidence. While further systematic studies are needed to explore the clinical neurobiological implications of OC phenomena in patients with schizophrenia, current evidence suggests that these patients require specific symptom assessment and individualized pharmacological and psychotherapeutic treatment interventions for optimal outcome.
机译:尽管多年来已经描述了精神分裂症中的强迫性(OC)现象,但近年来这种情况越来越受到关注。然而,精神分裂症中OC症状的临床和生物学意义仍然存在争议。尽管曾经认为精神分裂症中的OC症状很少发生,并且与更多的良性临床过程相关,但最近的研究表明,患病率更高,预后也较差。此外,根据新兴的临床证据,精神分裂症的OC亚组对传统抗精神病药物的治疗反应较差,但可能对辅助性抗OCD方案产生积极的反应。 虽然还需要进一步的系统研究来探索其临床意义。 OC现象对精神分裂症患者的神经生物学影响,目前的证据表明,这些患者需要特定的症状评估以及个性化的药物和心理治疗干预措施才能获得最佳结果。

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