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Development and Design of Next-Generation Head-Mounted Ambulatory Microdose Positron-Emission Tomography (AM-PET) System

机译:下一代头戴式门诊微剂量正电子发射断层扫描(AM-PET)系统的开发与设计

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摘要

Several applications exist for a whole brain positron-emission tomography (PET) brain imager designed as a portable unit that can be worn on a patient’s head. Enabled by improvements in detector technology, a lightweight, high performance device would allow PET brain imaging in different environments and during behavioral tasks. Such a wearable system that allows the subjects to move their heads and walk—the Ambulatory Microdose PET (AM-PET)—is currently under development. This imager will be helpful for testing subjects performing selected activities such as gestures, virtual reality activities and walking. The need for this type of lightweight mobile device has led to the construction of a proof of concept portable head-worn unit that uses twelve silicon photomultiplier (SiPM) PET module sensors built into a small ring which fits around the head. This paper is focused on the engineering design of mechanical support aspects of the AM-PET project, both of the current device as well as of the coming next-generation devices. The goal of this work is to optimize design of the scanner and its mechanics to improve comfort for the subject by reducing the effect of weight, and to enable diversification of its applications amongst different research activities.
机译:全脑正电子发射断层扫描(PET)脑成像仪有多种应用,这些成像仪设计为可戴在患者头部的便携式装置。借助检测器技术的改进,轻巧,高性能的设备将允许在不同环境中和行为任务期间对PET脑成像。目前正在开发这样一种可穿戴系统,使受试者可以移动自己的头和行走—动态微剂量PET(AM-PET)。该成像仪将有助于测试对象执行选定的活动,例如手势,虚拟现实活动和步行。对这种轻便型移动设备的需求导致了概念验证便携式头戴式设备的构造,该设备使用了十二个硅光电倍增管(SiPM)PET模块传感器,该传感器内置在一个小环中,可安装在头部周围。本文着重于AM-PET项目的机械支撑方面的工程设计,包括当前设备以及即将推出的下一代设备。这项工作的目的是优化扫描仪及其机械的设计,以通过减轻重量的影响来提高受试者的舒适度,并使其在不同研究活动中的应用多样化。

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