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首页> 美国卫生研究院文献>The Journal of Spinal Cord Medicine >Auricular acupuncture for spinal cord injury related neuropathic pain: a pilot controlled clinical trial
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Auricular acupuncture for spinal cord injury related neuropathic pain: a pilot controlled clinical trial

机译：耳针疗法治疗脊髓损伤相关的神经性疼痛：一项中试对照临床试验

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>Objective: To obtain preliminary data on the effects of an auricular acupuncture protocol, Battlefield Acupuncture (BFA), on self-reported pain intensity in persons with chronic Spinal Cord Injury (SCI) and neuropathic pain.>Design: Pilot randomized delayed entry single center crossover clinical trial at an outpatient rehabilitation and integrative medicine hospital center.>Methods: Chronic (> one year post injury) ASIA impairment scale A through D individuals with SCI with injury level from C3 through T12 and below level neuropathic pain with at least five on the Numeric Rating Scale (NRS) were recruited. Twenty-four subjects were randomized to either an eight-week once weekly ten-needle BFA protocol (n = 13) or to a waiting list followed by the BFA protocol (n = 11).>Outcome measures: The primary outcome measure was change in the pain severity NRS. Secondary outcome was the Global Impression of Change.>Results: Demographically there were no significant differences between groups. Mean pain scores at baseline were higher in acupuncture than control subjects (7.75 ± 1.54 vs. 6.25 ± 1.04, P = 0.027). Although both groups reported significant reduction in pain during the trial period, the BFA group reported more pain reduction than the delayed entry group (average change in NRS at eight weeks –2.92 ± 2.11 vs. −1.13 ± 2.14, P = 0.065). There was a significant difference in groups when a group-by-time interaction in a mixed-effect repeated measures model (P = 0.014).>Conclusion: This pilot study has provided proof of concept that BFA has clinically meaningful effect on the modulation of SCI neuropathic pain.
机译：>目的：要获得有关耳针疗法（战地针灸）对慢性脊髓损伤（SCI）和神经性疼痛患者自我报告的疼痛强度影响的初步数据。 >设计：在门诊康复和中西医结合医院中心进行的随机延迟进入单中心交叉临床试验。>方法：慢性（受伤后一年以上）ASIA损伤量表，从A到D SCI的损伤水平从C3到T12，且神经病理性疼痛低于水平，且其数字评分量表（NRS）至少为5。 24名受试者被随机分为8周一次，每周一次的十针BFA方案（n = 13）或等待名单，随后是BFA方案（n = 11）。>结果测量：主要结局指标是疼痛严重程度NRS的变化。次要结果是变化的全球印象。>结果：人口统计学上两组之间没有显着差异。针刺时基线时的平均疼痛评分高于对照组（7.75±1.54 vs. 6.25±1.04，P = 0.027）。尽管两组都报告了试验期间疼痛的明显减轻，但BFA组的疼痛减轻比延迟进入组更大（八周时NRS的平均变化为–2.92±2.11，-1.13±2.14，P = 0.065）。当在混合效应重复测量模型中进行逐组交互时，各组之间存在显着差异（P = 0.014）。>结论：这项初步研究提供了BFA在临床上具有概念性的证据对SCI神经性疼痛的调节具有重要意义。

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