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Successful Interventional Treatment for Arterioportal Fistula Caused by Radiofrequency Ablation for Hepatocellular Carcinoma

机译:射频消融治疗肝癌的门静脉瘘的成功介入治疗

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摘要

Radiofrequency ablation (RFA) is commonly used as a treatment for small hepatocellular carcinoma (HCC). Although several complications such as intraperitoneal bleeding are often observed after RFA, hepatic arterioportal fistula (APF) is a less frequently occurring complication. In this study, we describe two cases of APF caused by RFA, which was successfully occluded by an interventional approach. Case 1 involved a 68-year-old man with solitary HCC in segment VIII of the liver. Both contrast-enhanced computed tomography and color Doppler sonography indicated an APF between the anterosuperior branch of the right hepatic artery (A8) and the portal branch (P8). Concordant with these findings, digital subtraction angiography (DSA) revealed an APF in segment VIII of the liver. Subsequently, the APF was successfully occluded by transarterial embolization (TAE) using gelatin sponge particles. Case 2 involved a 67-year-old man with solitary HCC in segment VII of the liver. Although he developed obstructive jaundice because of hemobilia after RFA, it was improved by endoscopic nasobiliary drainage and the systemic administration of antibiotics. In addition, color Doppler sonography revealed a disturbed flow of the right branch of the portal vein. Similar to case 1, DSA showed an APF between A8 and P8. The APF was successfully embolized by TAE using microcoils. In conclusion, it appears that the formation of APF should be checked after RFA. It is preferable to treat RFA-induced APF promptly by an interventional approach to avoid secondary complications such as portal hypertension and liver dysfunction.
机译:射频消融(RFA)通常用于治疗小肝细胞癌(HCC)。尽管RFA术后常观察到多种并发症,例如腹膜内出血,但肝动门静脉瘘(APF)是较不常见的并发症。在这项研究中,我们描述了由RFA引起的两例APF病例,这些病例已通过干预方法成功闭塞。病例1涉及一名68岁的男性,在肝脏VIII段患有单独的HCC。对比增强计算机断层扫描和彩色多普勒超声检查均显示右肝动脉上支(A8)和门脉(P8)之间的APF。与这些发现一致,数字减影血管造影(DSA)显示了肝脏VIII段的APF。随后,使用明胶海绵颗粒经动脉栓塞(TAE)成功阻塞了APF。案例2涉及一名67岁的男性,在肝脏VII段患有单独的HCC。尽管他因RFA引起的胆道疾病而发展为梗阻性黄疸,但通过内镜鼻胆管引流术和全身性使用抗生素可以改善这种情况。此外,彩色多普勒超声检查显示门静脉右分支的血流不畅。与情况1相似,DSA显示A8和P8之间的APF。 TAE使用微线圈成功将APF栓塞。总之,似乎应该在RFA之后检查APF的形成。最好通过介入方法迅速治疗RFA诱导的APF,以避免继发性并发症,例如门脉高压和肝功能障碍。

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