Comparison of once-daily nifedipine controlled-release with twice-daily nifedipine retard in the treatment of essential hypertension

机译：每日两次硝苯地平控释与每日两次硝苯地平延缓治疗原发性高血压的比较

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摘要

AimsNifedipine is a short-acting calcium antagonist formulated into several different oral preparations, each of which may have different effects on haemodynamics and autonomic nervous function. We compared the effects of nifedipine controlled-release (CR) and nifedipine retard on 24-h blood pressure, heart rate, rate–pressure product, and power spectral measures of heart rate variability in patients with essential hypertension.

机译：AimsNifedipine是一种短效钙拮抗剂，配制成几种不同的口服制剂，每种制剂可能对血流动力学和自主神经功能有不同的作用。我们比较了硝苯地平控释（CR）和硝苯地平延缓对原发性高血压患者24小时血压，心率，心率-血压乘积以及心率变异性功率谱测量的影响。

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期刊名称 British Journal of Clinical Pharmacology
作者
Junichi Minami; Atsushi Numabe; Norikazu Andoh; Naohiko Kobayashi; Shigeo Horinaka; Toshihiko Ishimitsu; Hiroaki Matsuoka;
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作者单位

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年(卷),期 2004(57),5
年度 2004
页码 632–639
总页数 8
原文格式 PDF
正文语种
中图分类药学;
关键词
autonomic nervous function blood pressure heart rate nifedipine controlled-release nifedipine retard;

机译：自主神经功能;血压;心率;硝苯地平控释;硝苯地平延缓;

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专利

1. Comparison of once-daily nifedipine controlled-release with twice-daily nifedipine retard in the treatment of essential hypertension. [J] . Minami J, Numabe A, Andoh N, British Journal of Clinical Pharmacology . 2004,第5期

机译：每日两次硝苯地平控释与每日两次硝苯地平延缓治疗原发性高血压的比较。
2. A comparison of the effects of two modified release preparations of nifedipine-nifedipine retard 10 mg twice daily and nifedipine GITS 20 mg once daily--in the treatment of mild to moderate hypertension. [J] . Kirby BJ, Kitchin NR International journal of clinical practice . 1999,第5期

机译：两种缓释硝苯地平-硝苯地平缓释片（每日两次）和硝苯地平GITS（每日20次）在轻度至中度高血压中的两种疗效比较。
3. Nifedipine controlled-release 40 mg b.i.d. in Japanese patients with essential hypertension who responded insufficiently to nifedipine controlled-release 40 mg q.d.: a phase III, randomized, double-blind and parallel-group study [J] . Kazuaki Shimamoto, Naoyuki Hasebe, Sadayoshi Ito, Hypertension research: Official journal of the Japanese Society of Hypertension . 2014,第1期

机译：硝苯地平控释40 mg b.i.d.日本原发性高血压患者对硝苯地平控释40 mg q.d.反应不充分：III期，随机，双盲和平行组研究
4. Once-daily Nadroparin Versus Twice-daily Nadroparin in the Treatment of Patients with Acute Coronary Syndromes: The SAFRAX Study [C] . V. Hricak, A. Leizorovic International Congress on Thrombosis . 2006

机译：每日一日奈多林与每次每日Nadroparin治疗患者急性冠状动脉综合征患者：Safrax研究
5. Development of a three compartment oral sustained release delivery system for nifedipine: An in vitro and in vivo comparison with an osmotic pump delivery system, in the dog. [D] . Anwar, Hanan Sami. 1997

机译：硝苯地平三腔口服缓释递送系统的开发：在犬中与渗透泵递送系统的体外和体内比较。
6. Long-term safety and efficacy of high-dose controlled-release nifedipine (80 mg per day) in Japanese patients with essential hypertension [O] . Kazuaki Shimamoto, Masafumi Kimoto, Yoshimi Matsuda, -1

机译：大剂量控释硝苯地平（每天80μmg/天）对日本原发性高血压患者的长期安全性和有效性
7. Comparison of once-daily nifedipine controlled-release with twice-daily nifedipine retard in the treatment of essential hypertension [O] . Minami, Junichi, Numabe, Atsushi, Andoh, Norikazu, 2004

机译：每日两次硝苯地平控释与每日两次硝苯地平延缓治疗原发性高血压的比较
8. Nifedipine for Treatment of High Altitude Pulmonary Edema [R] . Hackett, P. H., Roach, R. C., Greene, E. R., 1992

机译：硝苯地平治疗高原肺水肿

Comparison of once-daily nifedipine controlled-release with twice-daily nifedipine retard in the treatment of essential hypertension

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