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Influence of severity of illness on neutrophil gelatinase-associated lipocalin performance as a marker of acute kidney injury: a prospective cohort study of patients with sepsis

机译：疾病严重程度对中性粒细胞明胶酶相关脂质运载蛋白性能作为急性肾损伤标志物的影响：败血症患者的前瞻性队列研究

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摘要

BackgroundThe role of neutrophil gelatinase-associated lipocalin (NGAL) as a diagnostic marker for acute kidney injury (AKI) in sepsis is still debated. We hypothesized that in sepsis, the performance of serum(s) and urinary(u) NGAL can be negatively impacted by severity of illness and inflammation, and that both uNGAL and sNGAL levels can be increased regardless of presence of AKI.

机译：背景嗜中性粒细胞明胶酶相关脂质运载蛋白（NGAL）作为脓毒症中急性肾损伤（AKI）的诊断标志物的作用仍在争论中。我们假设在脓毒症中，疾病和炎症的严重性会对血清和尿NGAL的性能产生负面影响，而无论AKI的存在，uNGAL和sNGAL的水平均可升高。

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期刊名称 BMC Nephrology
作者
Jill Vanmassenhove; Griet Glorieux; Norbert Lameire; Eric Hoste; Annemieke Dhondt; Raymond Vanholder; Wim Van Biesen;
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作者单位

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年(卷),期 2015(16),-1
年度 2015
页码 18
总页数 10
原文格式 PDF
正文语种
中图分类泌尿科学（泌尿生殖系疾病）;小儿泌尿科学;肾疾病;
关键词
Sepsis Acute kidney injury NGAL;

机译：败血症;急性肾损伤;NGAL;

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1. Influence of severity of illness on neutrophil gelatinase-associated lipocalin performance as a marker of acute kidney injury: a prospective cohort study of patients with sepsis [J] . Jill Vanmassenhove, Griet Glorieux, Norbert Lameire, BMC Nephrology . 2015,第1期

机译：疾病严重程度对中性粒细胞明胶酶相关脂质运载蛋白作为急性肾损伤标志物的影响：败血症患者的前瞻性队列研究
2. Urine neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in critically ill children: a prospective cohort study [J] . Michael Zappitelli, Kimberly K Washburn, Ayse A Arikan, Critical care : . 2007,第4期

机译：尿中性粒细胞明胶酶相关脂质运载蛋白是危重儿童急性肾损伤的早期标志物：一项前瞻性队列研究
3. Urine neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in critically ill children: a prospective cohort study [J] . Michael Zappitelli, Kimberly K Washburn, Ayse A Arikan, Critical care : . 2007,第4期

机译：尿中性粒细胞明胶酶相关脂质运载蛋白是危重儿童急性肾损伤的早期标志物：一项前瞻性队列研究
4. Expression of Human Neutrophil Gelatinase-Associated Lipocalin (Ngal) on Serum and Urine Sample of Pre Dialysis Kidney Failure Patients [C] . Retty Ratnawati, Tinny Endang Hernowati, Nurina Titisari, International Conference in One Health . 2018

机译：血清血清血清和尿液样品的人性化粒细胞凝胶酶相关脂素（NGAL）的表达
5. Subclinical albuminuria, beta trace protein, neutrophil gelatinase associated lipocalin, and kidney injury molecule-1 and risk of coronary heart disease, chronic kidney disease, and death [D] . Bhavsar, Nrupen A. 2010

机译：亚临床蛋白尿，β微量蛋白，中性粒细胞明胶酶相关的脂钙蛋白和肾损伤分子1以及冠心病，慢性肾脏病和死亡的风险
6. Diagnostic performance of plasma and urine neutrophil gelatinase-associated lipocalin, cystatin C, and creatinine for acute kidney injury in burn patients: A prospective cohort study [O] . Youngmin Kim, Yong Suk Cho, Dohern Kym, 2012

机译：血浆和尿液中性粒细胞明胶酶相关的脂蛋白，半胱氨酸蛋白酶抑制剂C和肌酐对烧伤患者急性肾损伤的诊断性能：一项前瞻性队列研究
7. Influence of severity of illness on neutrophil gelatinase-associated lipocalin performance as a marker of acute kidney injury: a prospective cohort study of patients with sepsis [O] . 2015

机译：疾病严重程度对中性粒细胞明胶酶相关脂质运载蛋白性能作为急性肾损伤标志物的影响：败血症患者的前瞻性队列研究

Influence of severity of illness on neutrophil gelatinase-associated lipocalin performance as a marker of acute kidney injury: a prospective cohort study of patients with sepsis

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