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首页> 美国卫生研究院文献>BioResearch Open Access >Knowledge of Cervical Cancer and Acceptability of Prevention Strategies Among Human Papillomavirus-Vaccinated and Human Papillomavirus-Unvaccinated Adolescent Women in Eldoret Kenya
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Knowledge of Cervical Cancer and Acceptability of Prevention Strategies Among Human Papillomavirus-Vaccinated and Human Papillomavirus-Unvaccinated Adolescent Women in Eldoret Kenya

机译：肯尼亚埃尔多雷特的人乳头瘤病毒疫苗接种和人乳头瘤病毒未接种疫苗的青春期妇女宫颈癌的知识和预防策略的可接受性

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Cervical cancer is a critical public health concern in sub-Saharan Africa. Adolescents are key targets in primary prevention strategies. Following a human papillomavirus (HPV) vaccination initiative (Gardasil) in Eldoret, Kenya, the knowledge and source of information of cervical cancer and acceptance of prevention strategies among vaccinated and unvaccinated adolescents were evaluated. A cross-sectional comparative study enrolled 60 vaccinated and 120 unvaccinated adolescent women. Institutional ethical approval was obtained and signed consent was obtained from the parents. Data collection was performed using interviewer-administered questionnaires derived from factual statements based on information from print material used for community sensitization on cervical cancer. The median age of the participants was 14.0 years (interquartile range [IQR] = 13.0–15.0). Of 60 vaccinated adolescents, 56 (93.3%) had heard of the HPV vaccine compared with 6 (5%) of unvaccinated participants (p < 0.001). Of 60 vaccinated participants, 58 (96.7%) had heard of cervical cancer compared with 61 (50.8%) unvaccinated participants (p < 0.001). Both cohorts identified the school as the main source of information for cervical cancer. The two groups also showed similarity in their selection of cervical cancer prevention strategies acceptable to them such as delaying sexual debut, limiting number of sexual partners, and use of condoms for protection against sexually transmitted infections. Of 120 unvaccinated participants, 63.7% expressed willingness to be vaccinated. Exposure to the HPV vaccine was associated with a higher knowledge of cervical cancer. The adolescents predominantly rely on the school for health information. Both cohorts of adolescents showed remarkable acceptability for cervical cancer prevention strategies.
机译：宫颈癌是撒哈拉以南非洲地区至关重要的公共卫生问题。青少年是初级预防策略的主要目标。在肯尼亚埃尔多雷特市开展人类乳头瘤病毒（HPV）疫苗接种计划（Gardasil）之后，评估了接种疫苗和未接种疫苗的青少年对子宫颈癌的知识和信息来源以及接受的预防策略。一项横断面比较研究招募了60名接种疫苗的女性和120名未接种疫苗的青春期妇女。获得了机构伦理上的批准，并获得了父母的同意。数据收集是使用采访者管理的问卷进行的，问卷是基于基于社区敏感性宫颈癌印刷材料的事实陈述而从事实陈述中得出的。参与者的中位年龄为14.0岁（四分位间距[IQR] = 13.0-15.0）。在60名接种疫苗的青少年中，有56名（93.3％）听说过HPV疫苗，而未接种疫苗的参与者中有6名（5％）（p <0.001）。在60名接种疫苗的参与者中，有58名（96.7％）听说过宫颈癌，而61名未接种疫苗的参与者（50.8％）（p <0.001）。两个队列都将学校确定为宫颈癌的主要信息来源。两组在选择可接受的子宫颈癌预防策略上也表现出相似性，例如延迟性行为首次出现，限制性伴侣的数量以及使用避孕套来预防性传播感染。在120名未接种疫苗的参与者中，有63.7％的人表示愿意接种疫苗。接触HPV疫苗与宫颈癌的知识增高有关。青少年主要依靠学校获得健康信息。两组青少年均显示出对宫颈癌预防策略的显着接受性。

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