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Evaluation of the Endothelial Cell Density and the Central Corneal Thickness in Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma

机译:假性剥脱综合征和假性剥脱性青光眼的内皮细胞密度和角膜中央厚度的评估

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摘要

Purpose. Evaluation of central corneal thickness (CCT) and endothelial cell density (ECD) in patients with senile cataract and coexisting pseudoexfoliation (PEX) syndrome with glaucoma (PEXG) and without glaucoma using specular microscopy. Participants and Methods. The study included 122 patients (217 eyes). In this group of patients we identified 133 eyes with PEX syndrome (65 with glaucoma, 68 without glaucoma) and 84 eyes without PEX syndrome. ECD and CCT were measured in each eye by specular microscopy. Results. ECD in eyes with PEX syndrome without glaucoma (2297 ± 359 cell/mm2) and in eyes with PEXG (2241 ± 363 cell/mm2) was lower than in the control group (2503 ± 262 cell/mm2) (P < 0.001). CCT in eyes with PEXG (508.2 ± 32.6 μm) was thinner than in eyes with PEX syndrome without glaucoma (529.7 ± 30.3 μm) and control group (527.7 ± 29.4 μm) (P < 0.001). Conclusions. This research shows that in eyes with PEX syndrome, both with and without glaucoma, ECD was statistically significantly lower than in the control group. In patients with PEXG, CCT was statistically significantly thinner than in the PEX syndrome and control group.
机译:目的。使用镜面显微镜评估患有老年性白内障并伴有青光眼(PEXG)和无青光眼的老年性白内障并存假性剥脱(PEX)综合征的患者的中央角膜厚度(CCT)和内皮细胞密度(ECD)。参加者和方法。该研究包括122名患者(217只眼)。在这组患者中,我们确定了133眼患有PEX综合征(65例患有青光眼,68例未患有青光眼)和84眼没有PEX综合征。通过镜面显微镜在每只眼睛中测量ECD和CCT。结果。没有青光眼的PEX综合征眼的ECD(2297±359 cell / mm 2 )和患有PEXG的眼(2241±363 cell / mm 2 )低于正常人。对照组(2503±262 cell / mm 2 )(P <0.001)。 PEXG眼(508.2±32.6μm)的CCT较无青光眼PEX综合征的眼(529.7±30.3μm)和对照组(527.7±29.4μm)薄(P <0.001)。结论。这项研究表明,在有或没有青光眼的PEX综合征眼中,ECD在统计学上均显着低于对照组。在PEXG患者中,CCT在统计学上明显比PEX综合征和对照组薄。

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