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Treatment of rats with Jiangzhi Capsule improves liquid fructose-induced fatty liver: modulation of hepatic expression of SREBP-1c and DGAT-2

机译：降脂胶囊治疗大鼠可改善果糖诱导的脂肪肝：调节SREBP-1c和DGAT-2的肝表达

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摘要

BackgroundJiangzhi Capsule is an Australian listed patented traditional Chinese medicine and has been used for management of lipid abnormalities over the past 10 years. To obtain a better understanding regarding Jiangzhi Capsule, the present study investigated the effects and underlying mechanisms of Jiangzhi Capsule on chronic fructose overconsumption-induced lipid abnormalities.

机译：背景技术姜枝胶囊是澳大利亚上市的专利中药，在过去的十年中一直用于脂质异常的治疗。为了更好地了解降脂胶囊，本研究调查了降脂胶囊对慢性果糖过量摄入引起的脂质异常的作用及其潜在机制。

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期刊名称 Journal of Translational Medicine
作者
Yuanyang Zhao; Yongquan Pan; Yifan Yang; Robert Batey; Jianwei Wang; Yuhao Li;
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作者单位

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年(卷),期 2015(13),-1
年度 2015
页码 174
总页数 12
原文格式 PDF
正文语种
中图分类医学史;
关键词
Acyl-coenzyme A:diacylglycerol acyltransferase Lipid Jiangzhi Capsule Liver Sterol regulatory element-binding protein-1c Triglyceride;

机译：酰基辅酶A：二甘油甘油酰基转移酶;脂质;降脂胶囊;肝脏;甾醇调节元素结合蛋白1c;甘油三酸酯;

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专利

1. Treatment of rats with Jiangzhi Capsule improves liquid fructose-induced fatty liver: modulation of hepatic expression of SREBP-1c and DGAT-2 [J] . Yuanyang Zhao, Yongquan Pan, Yifan Yang, Journal of Translational Medicine . 2015,第1期

机译：降脂胶囊对大鼠的治疗可改善果糖诱导的脂肪肝：调节SREBP-1c和DGAT-2的肝表达
2. Oleanolic Acid Diminishes Liquid Fructose-Induced Fatty Liver in Rats: Role of Modulation of Hepatic Sterol Regulatory Element-Binding Protein-lc-Mediated Expression of Genes Responsible for De Novo Fatty Acid Synthesis [J] . Changjin Liu, Ying Li, Guowei Zuo, Evidence-based complementary and alternative medicine: eCAM . 2013,第7期

机译：齐墩果酸减少大鼠中液体果糖诱导的脂肪肝：肝甾醇调节元件结合蛋白-lc介导负责从头脂肪酸合成的基因表达的调节作用。
3. Oleanolic Acid Diminishes Liquid Fructose-Induced Fatty Liver in Rats: Role of Modulation of Hepatic Sterol Regulatory Element-Binding Protein-lc-Mediated Expression of Genes Responsible for De Novo Fatty Acid Synthesis [J] . Changjin Liu, Ying Li, Guowei Zuo, Evidence-based complementary and alternative medicine: eCAM . 2013,第7期

机译：齐墩果酸减少大鼠中液体果糖诱导的脂肪肝：肝甾醇调节元件结合蛋白-lc介导负责从头脂肪酸合成的基因表达的调节作用。
4. Effects of osthole on protein expression of CYP7A1, DGAT2 and PPARα/γ in fat milk-induced fatty liver rats [C] . ZHANG Yan, XIE Mei-lin, XUE Jie, The 2nd International Conference on Bioinformatics and Biomedical Engineering(iCBBE 2008)(第二届生物信息与生物医学工程国际会议）论文集 . 2008

机译：蛇床子素对脂肪乳诱导的脂肪肝大鼠CYP7A1，DGAT2和PPARα/γ蛋白表达的影响
5. Adaptation to ethanol dysregulates hepatic miRNA expression and alters the dynamic response of miRNAs during liver regeneration [D] . Dippold, Rachael P. 2012

机译：适应乙醇会失调肝脏miRNA的表达并改变肝脏再生过程中miRNA的动态反应
6. Oleanolic Acid Diminishes Liquid Fructose-Induced Fatty Liver in Rats: Role of Modulation of Hepatic Sterol Regulatory Element-Binding Protein-1c-Mediated Expression of Genes Responsible for De Novo Fatty Acid Synthesis [O] . Changjin Liu, Ying Li, Guowei Zuo, 2013

机译：齐墩果酸减少大鼠液体果糖诱导的脂肪肝：肝甾醇调节元件结合蛋白-1 c介导负责从头脂肪酸合成基因的表达的调节作用。
7. Treatment of rats with Jiangzhi Capsule improves liquid fructose-induced fatty liver: modulation of hepatic expression of SREBP-1c and DGAT-2 [O] . Yuanyang Zhao, Yongquan Pan, Yifan Yang, 2015

机译：降脂胶囊治疗大鼠可改善果糖诱导的脂肪肝：调节SREBP-1c和DGAT-2的肝表达
8. Fatty liver dystrophy (fld) mutation: Developmentally related alterations in hepatic triglyceride metabolism and protein expression [R] . Reue, K. , Rehnmark, S. , Cohen, R. D. , 1997

机译：脂肪肝营养不良（fld）突变：肝脏甘油三酯代谢和蛋白质表达的发育相关改变

Treatment of rats with Jiangzhi Capsule improves liquid fructose-induced fatty liver: modulation of hepatic expression of SREBP-1c and DGAT-2

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