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首页> 美国卫生研究院文献>The American Journal of Clinical Nutrition >Replacing caloric beverages with water or diet beverages for weight loss in adults: main results of the Choose Healthy Options Consciously Everyday (CHOICE) randomized clinical trial
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Replacing caloric beverages with water or diet beverages for weight loss in adults: main results of the Choose Healthy Options Consciously Everyday (CHOICE) randomized clinical trial

机译：用水或减肥饮料代替卡路里饮料以减轻成年人的体重：每天选择健康选择意识（CHOICE）随机临床试验的主要结果

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>Background: Replacement of caloric beverages with noncaloric beverages may be a simple strategy for promoting modest weight reduction; however, the effectiveness of this strategy is not known.>Objective: We compared the replacement of caloric beverages with water or diet beverages (DBs) as a method of weight loss over 6 mo in adults and attention controls (ACs).>Design: Overweight and obese adults [n = 318; BMI (in kg/m2): 36.3 ± 5.9; 84% female; age (mean ± SD): 42 ± 10.7 y; 54% black] substituted noncaloric beverages (water or DBs) for caloric beverages (≥200 kcal/d) or made dietary changes of their choosing (AC) for 6 mo.>Results: In an intent-to-treat analysis, a significant reduction in weight and waist circumference and an improvement in systolic blood pressure were observed from 0 to 6 mo. Mean (±SEM) weight losses at 6 mo were −2.5 ± 0.45% in the DB group, −2.03 ± 0.40% in the Water group, and −1.76 ± 0.35% in the AC group; there were no significant differences between groups. The chance of achieving a 5% weight loss at 6 mo was greater in the DB group than in the AC group (OR: 2.29; 95% CI: 1.05, 5.01; P = 0.04). A significant reduction in fasting glucose at 6 mo (P = 0.019) and improved hydration at 3 (P = 0.0017) and 6 (P = 0.049) mo was observed in the Water group relative to the AC group. In a combined analysis, participants assigned to beverage replacement were 2 times as likely to have achieved a 5% weight loss (OR: 2.07; 95% CI: 1.02, 4.22; P = 0.04) than were the AC participants.>Conclusions: Replacement of caloric beverages with noncaloric beverages as a weight-loss strategy resulted in average weight losses of 2% to 2.5%. This strategy could have public health significance and is a simple, straightforward message. This trial was registered at as .
机译：>背景：用无热量饮料代替无热量饮料可能是促进适度减轻体重的简单策略；但是，该策略的效果尚不清楚。>目的：我们比较了以水或减肥饮料（DBs）代替卡路里饮料作为成年人6个月以上体重减轻的方法和注意力控制（ >设计：超重和肥胖的成年人[n = 318； BMI（kg / m 2 ）：36.3±5.9； 84％女性；年龄（平均±SD）：42±10.7 y； 54％的黑色]代替无热量饮料（水或DBs）（≥200 kcal / d）或在6个月内改变饮食选择（AC）。>结果：治疗分析，从0到6 mo观察到体重和腰围明显减少，收缩压得到改善。 DB组在6 mo时的平均（±SEM）重量损失为-2.5±0.45％，Water组为-2.03±0.40％，AC组为-1.76±0.35％；两组之间没有显着差异。 DB组在6 mo时实现5％体重减轻的机会大于AC组（OR：2.29； 95％CI：1.05，5.01； P = 0.04）。在水组中，相对于AC组，在6 mo（P = 0.019）时空腹血糖显着降低（P = 0.019），在3（P = 0.0017）和6（P = 0.049）mo时水合作用得到改善。在一项综合分析中，分配给饮料替代品的参与者达到5％体重减轻的可能性（OR：2.07； 95％CI：1.02，4.22； P = 0.04）是AC参与者的2倍。>结论：作为减肥策略，用非卡路里饮料代替卡路里饮料导致平均体重减轻2％至2.5％。该策略可能具有公共卫生意义，并且是一个简单，直接的信息。该审判的注册地址为。

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