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CD200R1 agonist attenuates glial activation inflammatory reactions and hypersensitivity immediately after its intrathecal application in a rat neuropathic pain model

机译：CD200R1激动剂在大鼠神经病理性疼痛模型中鞘内施用后立即减轻神经胶质激活炎症反应和超敏反应

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摘要

BackgroundInteraction of CD200 with its receptor CD200R has an immunoregulatory role and attenuates various types of neuroinflammatory diseases.

机译：背景技术CD200及其受体CD200R的相互作用具有免疫调节作用，可减轻各种类型的神经炎性疾病。

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期刊名称 Journal of Neuroinflammation
作者
Miriam Hernangómez; Ilona Klusáková; Marek Joukal; Ivana Hradilová-Svíženská; Carmen Guaza; Petr Dubový;
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作者单位

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年(卷),期 2016(13),-1
年度 2016
页码 43
总页数 15
原文格式 PDF
正文语种
中图分类神经科学;
关键词
Rat neuropathic pain model Sterile nerve constriction Neuroinflammation Activated glial cells Cytokines Modulation;

机译：大鼠神经性疼痛模型;不育神经收缩;神经炎症;胶质细胞活化;细胞因子;调节;

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专利

1. The imidazoline I-2 receptor agonist 2-BFI attenuates hypersensitivity and spinal neuroinflammation in a rat model of neuropathic pain [J] . Siemian Justin N., LaMacchia Zach M., Spreuer Vilma, Biochemical Pharmacology . 2018,第期

机译：咪唑啉I-2受体激动剂2-BFI在大鼠神经病疼痛模型中衰减过敏和脊髓神经炎症
2. Intrathecal administration of clonidine attenuates spinal neuroimmune activation in a rat model of neuropathic pain with existing hyperalgesia. [J] . Feng X, Zhang F, Dong R European Journal of Pharmacology: An International Journal . 2009,第1a3期

机译：鞘内注射可乐定可减轻现有痛觉过敏的神经性疼痛大鼠模型的脊髓神经免疫激活。
3. Intrathecal CART (55-102) attenuates hyperlagesia and allodynia in a mouse model of neuropathic but not inflammatory pain. [J] . Damaj MI, Zheng J, Martin BR, Peptides: An International Journal . 2006,第8期

机译：鞘内注射CART（55-102）可减轻神经性但不是炎症性疼痛的小鼠模型中的皮膜增生和异常性疼痛。
4. Intrathecal pump delivery system can be used as reservoir, for intermittent iv lidocaine for the treatment of neuropathic flank pain. [C] . Mavrocordatos P, Laverdiere M, Skouvaklis D, International Congress on Neuropathic Pain . 2010

机译：鞘内泵输送系统可用作水库，用于间歇性IV利多卡因，用于治疗神经病理侧面疼痛。
5. Trigeminal Neuropathic Pain in Rats: A Role for Thalamic Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Activity [D] . Doheny, Jason. 2020

机译：大鼠的三叉神经疗法疼痛：对丘脑超极化活性的循环核苷酸门控通道活性的作用
6. Mechanical hypersensitivity sympathetic sprouting and glial activation are attenuated by local injection of corticosteroid near the lumbar ganglion in a rat model of neuropathic pain [O] . Jing-Yi Li, Wenrui Xie, Judith A. Strong, -1

机译：机械过敏交感神经出芽和神经胶质细胞活化是通过局部注射附近的腰椎神经节皮质类固醇的神经性疼痛的大鼠模型衰减
7. CD200R1 agonist attenuates glial activation, inflammatory reactions, and hypersensitivity immediately after its intrathecal application in a rat neuropathic pain model [O] . Miriam Hernangómez, Ilona Klusáková, Marek Joukal, 2016

机译：CD200R1激动剂在大鼠神经病理性疼痛模型中鞘内施用后立即减轻神经胶质激活，炎症反应和超敏反应

CD200R1 agonist attenuates glial activation inflammatory reactions and hypersensitivity immediately after its intrathecal application in a rat neuropathic pain model

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