• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>Oncology Letters >Application of pirarubicin photosensitizer fluorescence cystoscopy in early detection of bladder cancer
【2h】

Application of pirarubicin photosensitizer fluorescence cystoscopy in early detection of bladder cancer

机译：吡柔比星光敏剂荧光膀胱镜在膀胱癌早期检测中的应用

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The aim of this study was to investigate the value of pirarubicin (THP) photosensitizer fluorescence cystoscopy for the early diagnosis of bladder cancer. From January 2012 to June 2015, 25 patients with painless gross hematuria, were injected with THP 15 min prior to surgery and subsequently underwent fluorescence cystoscopy examination. Locations of tumors were recorded and biopsies were performed (total of 109 biopsies) under white and fluorescence light guidance. Biopsies were conducted at the THP-positive and -negative areas under white light and THP-positive areas under fluorescence light. Positive rate of bladder tumor tissue at the THP-positive areas detected under fluorescence light was 92.86%. The sensitivity and specificity were 100 and 96.15%, respectively. The positive rate of tumor tissue at the THP-positive areas detected under white light was 70.97%. The sensitivity and specificity were 100 and 84.74%, respectively. Fifty biopsies taken at the THP-negative areas under white light were found to be non-urothelial carcinoma tumor lesions. Thus, applying (THP) photosensitizer fluorescence cystoscopy for early-period bladder cancer diagnosis is safe, effective and practical. It showed a high degree of specificity and a low rate of false positives. It was a convenient visual diagnostic method for the early detection of non-muscular invasive bladder cancer.
机译：这项研究的目的是研究吡柔比星（THP）光敏剂荧光膀胱镜检查对膀胱癌早期诊断的价值。从2012年1月至2015年6月，对25例无痛性血尿的患者在手术前15分钟注射了THP，随后进行了荧光膀胱镜检查。记录肿瘤的位置，并在白光和荧光灯的引导下进行活检（总共109次活检）。在白光下的THP阳性和阴性区域以及荧光下的THP阳性区域进行活检。在荧光灯下检测到的THP阳性区域的膀胱肿瘤组织的阳性率为92.86％。敏感性和特异性分别为100和96.15％。白光下THP阳性区域的肿瘤组织阳性率为70.97％。敏感性和特异性分别为100和84.74％。发现在白光下THP阴性区域进行的五十次活检是非尿路上皮癌肿瘤病变。因此，将（THP）光敏剂荧光膀胱镜检查用于早期膀胱癌的诊断是安全，有效和实用的。它显示出高度的特异性和较低的假阳性率。这是一种用于早期检测非肌肉浸润性膀胱癌的便捷的视觉诊断方法。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号