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Extramedullary plasmacytoma of the cricoid cartilage progressing to multiple myeloma: A case report

机译:环状软骨的髓外浆细胞瘤发展为多发性骨髓瘤:一例报告

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摘要

Extramedullary plasmacytoma (EMP) is an uncommon tumor of the plasma cells, and EMP of the cricoid cartilage is extremely rare The present study reports the rare case of a 43-year-old male complaining of hoarseness and dyspnea for over a year. Computed tomography imaging of the neck revealed an occupying lesion in the cricoid cartilage, and a diagnosis of EMP was subsequently confirmed by histopathological evaluation. The patient underwent surgery, but refused radiotherapy against medical advice. One year later, the patient was diagnosed with a recurrence of EMP via pathological examination and underwent a second surgery, however, radiotherapy was refused. After a further two years and four months, the patient presented with lumps in the neck, and was subsequently diagnosed with multiple myeloma. The patient received systematic chemotherapy in the hematology department; the patient’s general condition stabilized, and no further anemia, bone pain, infection or other discomfort was experienced. Solitary plasmacytoma of the cricoid cartilage is a rare lesion and compliance with radiotherapy following surgery may provide significant benefit in the treatment of this disease.
机译:髓外浆细胞瘤(EMP)是浆细胞的罕见肿瘤,环软骨的EMP极为罕见。本研究报告了43岁的男性因声音嘶哑和呼吸困难一年以上的罕见病例。颈部计算机断层扫描显像发现环软骨中有占位病变,随后通过组织病理学评估证实了EMP的诊断。该患者接受了手术,但拒绝接受医学建议的放疗。一年后,经病理检查诊断为EMP复发,并进行了第二次手术,但放疗被拒绝。再过两年零四个月后,患者颈部出现肿块,随后被诊断为多发性骨髓瘤。患者在血液科接受了系统化学疗法;患者的总体状况稳定了,没有进一步的贫血,骨痛,感染或其他不适感。环状软骨的孤立性浆细胞瘤是一种罕见的病变,手术后对放射疗法的依从性可能在治疗该疾病方面提供显着的益处。

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