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首页> 美国卫生研究院文献>Oncology Letters >Comparison of diagnostic values between CA125 combined with CA199 and ultrasound combined with CT in ovarian cancer
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Comparison of diagnostic values between CA125 combined with CA199 and ultrasound combined with CT in ovarian cancer

机译：CA125联合CA199与超声联合CT对卵巢癌的诊断价值比较

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Application values of CA125 combined with CA199 and ultrasound combined with computed tomography (CT) in the clinical diagnosis of ovarian cancer were compared. A retrospective analysis was performed on 168 ovarian cancer patients admitted to the Department of Gynecology in Jining No.1 People's Hospital from July 2013 to March 2016. Of the patients 107 with malignant tumors were in the malignant group, and 61 patients with benign tumors were in the benign group. Another 98 healthy controls in the same period were in the normal group. Chemiluminescence was used for the detection of levels of tumor markers CA125 and CA199 in the serum of all patients. CA125 combined with CA199 and color Doppler ultrasound combined with CT scan were used to diagnose and analyze the sensitivity, specificity, accuracy, and positive detection rate of ovarian cancer patients at different stages. The sensitivity, specificity and diagnostic coincidence rate of ultrasound combined with CT in the diagnosis of ovarian cancer were 97.20, 80.32 and 91.07%, respectively, which were significantly higher than the 92.52, 73.77 and 85.71% of serum CA125 combined with CA199. The positive detection rate of ultrasound combined with CT in the early diagnosis of ovarian cancer was 93.55%, higher than 83.87% of CA125 combined with CA199. The sensitivity, specificity, coincidence rate and positive detection rate of ultrasound combined with CT in the diagnosis were higher than those of CA125 combined with CA199. In the actual diagnosis process, these two diagnostic schemes can be selectively and comprehensively applied, so as to make a correct diagnosis, which is of great significance for reducing patient mortality.
机译：比较了CA125联合CA199，超声联合计算机断层扫描（CT）在卵巢癌临床诊断中的应用价值。回顾性分析2013年7月至2016年3月在济宁市第一人民医院妇科收治的168例卵巢癌患者。其中恶性肿瘤107例，良性肿瘤61例。在良性人群中。同期另98例健康对照组为正常组。化学发光法用于检测所有患者血清中肿瘤标志物CA125和CA199的水平。采用CA125联合CA199，彩色多普勒超声结合CT扫描对卵巢癌患者不同阶段的敏感性，特异性，准确性和阳性检出率进行诊断和分析。超声联合CT诊断卵巢癌的敏感性，特异性和诊断符合率分别为97.20、80.32和91.07％，明显高于血清CA125联合CA199的92.52、73.77和85.71％。超声联合CT对卵巢癌的早期诊断阳性率为93.55％，高于CA125联合CA199的83.87％。超声结合CT诊断的敏感性，特异性，符合率和阳性检出率均高于CA125和CA199。在实际的诊断过程中，可以有选择地，全面地应用这两种诊断方案，以进行正确的诊断，这对于降低患者的死亡率具有重要意义。

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