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Neurotrophin levels at admission did not change significantly upon alcohol deprivation and were positively correlated with the BMI and LDL levels

机译：酒精摄入不足时神经营养蛋白水平没有明显变化并且与BMI和LDL水平呈正相关

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摘要

BackgroundThe neurotrophins brain-derived neurotrophic factor (BDNF) and neurotrophic factor 3 (NT3) could play a role in addictive behavior. Interactions between BDNF and dopamine transmission influence the alcohol intake. It has been hypothesized that extensive alcohol consumption leads to diminished circulating BDNF levels and impaired BDNF-mediated protective mechanisms. What is more, alcohol dependency causes changes in lipid metabolism which in turn may influence the neurotrophin system.

机译：背景神经营养蛋白的脑源性神经营养因子（BDNF）和神经营养因子3（NT3）可能在成瘾行为中起作用。 BDNF和多巴胺传递之间的相互作用会影响酒精摄入量。据推测，大量饮酒会导致循环BDNF水平降低和BDNF介导的保护机制受损。而且，酒精依赖会导致脂质代谢发生变化，进而可能影响神经营养蛋白系统。

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期刊名称 Journal of Molecular Psychiatry
作者
Aurel Popa-Wagner; Karolina Furczyk; Joerg Richter; Gisela Irmisch; Johannes Thome;
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作者单位

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年(卷),期 2013(1),1
年度 2013
页码 20
总页数 7
原文格式 PDF
正文语种
中图分类精神病学;
关键词
Alcoholism Brain-derived neurotrophic factor Neurotrophin-derived factor 3 Detoxification Lipoproteins;

机译：酒精中毒;脑源性神经营养因子;神经营养蛋白源性因子3;排毒;脂蛋白;

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专利

1. Neurotrophin levels at admission did not change significantly upon alcohol deprivation and were positively correlated with the BMI and LDL levels [J] . Aurel Popa-Wagner, Karolina Furczyk, Joerg Richter, Journal of Molecular Psychiatry . 2013,第1期

机译：酒精摄入不足时，神经营养蛋白水平没有明显变化，并且与BMI和LDL水平呈正相关
2. Neurotrophin levels at admission did not change significantly upon alcohol deprivation and were positively correlated with the BMI and LDL levels [J] . Aurel Popa-Wagner, Karolina Furczyk, Joerg Richter, Journal of Molecular Psychiatry . 2013,第1期

机译：酒精摄入不足时，入院时的神经营养素水平无明显变化，并且与BMI和LDL水平呈正相关
3. Visceral and subcutaneous adipose tissue stearoyl-CoA desaturase-1 mRNA levels and fatty acid desaturation index positively correlate with BMI in morbidly obese women [J] . Mika Adriana, Kaska Lukasz, Korczynska Justyna, European Journal of Lipid Science and Technology . 2015,第7期

机译：病态肥胖妇女的内脏和皮下脂肪组织硬脂酰辅酶A去饱和酶1 mRNA水平和脂肪酸去饱和指数与BMI呈正相关
4. Prolactin levels are positively correlated with polychlorinated biphenyls (PCB) in cord serum [C] . L. Takser, J. Lafond, D. Mergler International Conference on Environmental Toxicology . 2006

机译：催乳素水平与脐带血清中的多氯联苯（PCB）呈正相关
5. Early effects of organophosphate compounds on in vitro intracellular signaling and levels of active neurotrophin receptors, and on in vivo neurotrophin concentrations [D] . Pomeroy-Black, Melinda Jane 2005

机译：有机磷酸盐化合物对体外细胞内信号传导和活性神经营养蛋白受体水平以及体内神经营养蛋白浓度的早期影响
6. Quantity of alcohol drinking positively correlates with serum levels of endotoxin and markers of monocyte activation [O] . Suthat Liangpunsakul, Evelyn Toh, Ruth A. Ross, -1

机译：饮酒量与血清内毒素水平和单核细胞活化标志物呈正相关
7. Neurotrophin levels at admission did not change significantly upon alcohol deprivation and were positively correlated with the BMI and LDL levels [O] . Aurel Popa-Wagner, Karolina Furczyk, Joerg Richter, 2013

机译：酒精摄入不足时，神经营养蛋白水平没有明显变化，并且与BMI和LDL水平呈正相关

Neurotrophin levels at admission did not change significantly upon alcohol deprivation and were positively correlated with the BMI and LDL levels

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