Neurotrophin levels at admission did not change significantly upon alcohol deprivation and were positively correlated with the BMI and LDL levels

Aurel Popa-Wagner; Karolina Furczyk; Joerg Richter; Gisela Irmisch; Johannes Thome

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Neurotrophin levels at admission did not change significantly upon alcohol deprivation and were positively correlated with the BMI and LDL levels

机译：酒精摄入不足时，神经营养蛋白水平没有明显变化，并且与BMI和LDL水平呈正相关

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Background The neurotrophins brain-derived neurotrophic factor (BDNF) and neurotrophic factor 3 (NT3) could play a role in addictive behavior. Interactions between BDNF and dopamine transmission influence the alcohol intake. It has been hypothesized that extensive alcohol consumption leads to diminished circulating BDNF levels and impaired BDNF-mediated protective mechanisms. What is more, alcohol dependency causes changes in lipid metabolism which in turn may influence the neurotrophin system.

机译：背景神经营养因子脑源性神经营养因子（BDNF）和神经营养因子3（NT3）可能在成瘾行为中起作用。 BDNF和多巴胺传递之间的相互作用会影响酒精摄入量。据推测，大量饮酒会导致循环BDNF水平降低和BDNF介导的保护机制受损。而且，酒精依赖会导致脂质代谢发生变化，进而可能影响神经营养蛋白系统。

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《Journal of Molecular Psychiatry》 |2013年第1期|1-7|共7页
作者
Aurel Popa-Wagner; Karolina Furczyk; Joerg Richter; Gisela Irmisch; Johannes Thome;
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Alcoholism Brain-derived neurotrophic factor Neurotrophin-derived factor 3 Detoxification Lipoproteins;

机译：酒精中毒脑源性神经营养因子Neurotrophin源性因子3解毒脂蛋白;

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1. Neurotrophin levels at admission did not change significantly upon alcohol deprivation and were positively correlated with the BMI and LDL levels [J] . Aurel Popa-Wagner, Karolina Furczyk, Joerg Richter, Journal of Molecular Psychiatry . 2013,第1期

机译：酒精摄入不足时，入院时的神经营养素水平无明显变化，并且与BMI和LDL水平呈正相关
2. Visceral and subcutaneous adipose tissue stearoyl-CoA desaturase-1 mRNA levels and fatty acid desaturation index positively correlate with BMI in morbidly obese women [J] . Mika Adriana, Kaska Lukasz, Korczynska Justyna, European Journal of Lipid Science and Technology . 2015,第7期

机译：病态肥胖妇女的内脏和皮下脂肪组织硬脂酰辅酶A去饱和酶1 mRNA水平和脂肪酸去饱和指数与BMI呈正相关
3. Serum RBP4 positively correlates with triglyceride level but not with BMI, fat mass and insulin resistance in healthy obese and non-obese individuals [J] . Korek Emilia, Gibas-Dorna Magdalena, Checinska-Maciejewska Zuzanna, Biomarkers . 2018,第1a8期

机译：健康肥胖者和非肥胖者的血清RBP4与甘油三酯水平呈正相关，与BMI，脂肪量和胰岛素抵抗无关
4. Prolactin levels are positively correlated with polychlorinated biphenyls (PCB) in cord serum [C] . L. Takser, J. Lafond, D. Mergler International Conference on Environmental Toxicology . 2006

机译：催乳素水平与脐带血清中的多氯联苯（PCB）呈正相关
5. Early effects of organophosphate compounds on in vitro intracellular signaling and levels of active neurotrophin receptors, and on in vivo neurotrophin concentrations [D] . Pomeroy-Black, Melinda Jane 2005

机译：有机磷酸盐化合物对体外细胞内信号传导和活性神经营养蛋白受体水平以及体内神经营养蛋白浓度的早期影响
6. Neurotrophin levels at admission did not change significantly upon alcohol deprivation and were positively correlated with the BMI and LDL levels [O] . Aurel Popa-Wagner, Karolina Furczyk, Joerg Richter, 2013

机译：酒精摄入不足时神经营养蛋白水平没有明显变化并且与BMI和LDL水平呈正相关
7. Neurotrophin levels at admission did not change significantly upon alcohol deprivation and were positively correlated with the BMI and LDL levels [O] . Aurel Popa-Wagner, Karolina Furczyk, Joerg Richter, 2013

机译：酒精摄入不足时，神经营养蛋白水平没有明显变化，并且与BMI和LDL水平呈正相关

Neurotrophin levels at admission did not change significantly upon alcohol deprivation and were positively correlated with the BMI and LDL levels

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