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Non-directed bronchial lavage is a safe method for sampling therespiratory tract in critically ill patient

机译:非定向性支气管灌洗是一种安全的取样方法危重病人的呼吸道

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摘要

Ventilated patients are at risk of acquiring ventilator-associated pneumonia. Various techniques are available for diagnosing ventilator-associated pneumonia including bronchoalveolar lavage, protected specimen brush and non-directed bronchoalveolar lavage. There is a paucity of evidence regarding the safety profile of these techniques, particularly non-directed bronchoalveolar lavage. This service evaluation aimed to establish whether non-directed bronchoalveolar lavage is a safe procedure. A prospective service evaluation of non-directed bronchoalveolar lavage on our adult intensive care unit was undertaken by a senior physiotherapist trained into carrying out the procedure, measuring pre- and post-procedure vital signs including heart rate (HR), tidal volume (VT), systolic blood pressure (SBP) and pulse oximetry (SpO2). Eighty-five episodes in 41 patients were included in the evaluation. There was a statistically significant difference between pre- and immediately post-procedure recordings for all vital signs measure. HR (min-1), means (SD) 87.1 (16.4), 91.5 (16.5), 87.5 (15.9), 87.7 (15.7) respectively pre, immediately, 5 min after and 30 min after procedure (P < 0.01). SBP mmHg, means (SD) 133.9 (26.1), 142.1(25.6), 136.9 (25.3), 134.8 (23.4) pre, immediately, 5 min and 30 min afterprocedure (P < 0.01). VT mL, median (range) 0.523(0.118–1.180), 0.512 (0.131–1.05), 0.519 (0.104–0.95), 0.534 (0.110–1.080) eachpre, immediately, 5 min and 30 min post procedure(P < 0.05). SpO2 %, median (range) 98 (89–100),100 (96–100), 98 (92–100), 97 (90–100) again each pre-, immediately post, 5 and30 min post-procedure time-points (P < 0.0001). Thestatistically significant difference was not detected between pre-, 5 or 30 minpost-procedure time-points. None of the changes observed were clinicallysignificant and no untoward events happened to any of the subjects included.Non-directed bronchoalveolar lavage is a safe and inexpensive procedure that canbe carried out easily in an intensive care setting by a trained physiotherapist,avoiding the need for invasive bronchoscopy.
机译:通气患者有患呼吸机相关性肺炎的风险。有多种技术可用于诊断呼吸机相关性肺炎,包括支气管肺泡灌洗,保护标本刷和非定向性支气管肺泡灌洗。关于这些技术,特别是非定向性支气管肺泡灌洗的安全性资料很少。该服务评估旨在确定非定向支气管肺泡灌洗是否安全。由一名资深物理治疗师对我们的成人重症监护室进行的非定向性支气管肺泡灌洗进行前瞻性服务评估,该专家经过培训可以执行该程序,测量术前和术后的生命体征,包括心率(HR),潮气量(VT) ,收缩压(SBP)和脉搏血氧饱和度(SpO2)。该评估包括41例患者中的85例。对于所有生命体征指标,术前和术后立即记录之间在统计学上有显着差异。 HR(min -1 ),平均(SD)分别在手术前,手术后,手术后5分钟和手术后30分钟(分别)分别为87.1(16.4),91.5(16.5),87.5(15.9),87.7(15.7) (P <0.01)。 SBP mmHg,平均值(SD)133.9(26.1),142.1(25.6),136.9(25.3),134.8(23.4)前,立即,后5分钟和30分钟后程序(P <0.01)。 VT毫升,中位数(范围)0.523(0.118-1.180),0.512(0.131-1.05),0.519(0.104-0.95),0.534(0.110-1.080)手术前,立即,5分钟和30分钟后(P <0.05)。 SpO2%,中位数(范围)98(89–100),每次之前,立即发布,再分别发布100(96–100),98(92–100),97(90–100),5和手术后30分钟(P <0.0001)。的在5分钟或30分钟之前未检测到统计学上的显着差异手术后的时间点。临床上观察到的变化均未发现重大且没有不幸事件发生在所包括的任何受试者上。非定向支气管肺泡灌洗是一种安全,廉价的手术,可以由受过训练的物理治疗师在重症监护室中轻松进行,避免了有创支气管镜检查。

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