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Convergent recruitment of TALE homeodomain life cycle regulators to direct sporophyte development in land plants and brown algae

机译:集中招聘TALE同源域生命周期调节剂来指导陆地植物和褐藻中孢子体的发育

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摘要

Three amino acid loop extension homeodomain transcription factors (TALE HD TFs) act as life cycle regulators in green algae and land plants. In mosses these regulators are required for the deployment of the sporophyte developmental program. We demonstrate that mutations in either of two TALE HD TF genes, OUROBOROS or SAMSARA, in the brown alga Ectocarpus result in conversion of the sporophyte generation into a gametophyte. The OUROBOROS and SAMSARA proteins heterodimerise in a similar manner to TALE HD TF life cycle regulators in the green lineage. These observations demonstrate that TALE-HD-TF-based life cycle regulation systems have an extremely ancient origin, and that these systems have been independently recruited to regulate sporophyte developmental programs in at least two different complex multicellular eukaryotic supergroups, Archaeplastida and Chromalveolata.
机译:在绿藻和陆地植物中,三个氨基酸环延伸同源域转录因子(TALE HD TF)充当生命周期调节剂。在苔藓中,这些调节剂是孢子体发育计划的部署所必需的。我们证明了在棕色藻类鳞茎中的两个TALE HD TF基因,OUROBOROS或SAMSARA中的突变会导致孢子体转化成配子体。 OUROBOROS和SAMSARA蛋白的异源二聚体与绿色谱系中的TALE HD TF生命周期调节剂相似。这些观察结果表明,基于TALE-HD-TF的生命周期调控系统具有极其古老的渊源,并且已独立招募这些系统来调控至少两个不同的复杂多细胞真核超群Archaeplastida和Chromalveolata中的孢子体发育程序。

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