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Contemporary Understanding of miRNA-Based Regulation of Secondary Metabolites Biosynthesis in Plants

机译：基于miRNA的植物次生代谢物生物合成调控的当代理解。

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Plant's secondary metabolites such as flavonoids, terpenoids, and alkaloids etc. are known for their role in the defense against various insects-pests of plants and for medicinal benefits in human. Due to the immense biological importance of these phytochemicals, understanding the regulation of their biosynthetic pathway is crucial. In the recent past, advancement in the molecular technologies has enabled us to better understand the proteins, enzymes, genes, etc. involved in the biosynthetic pathway of the secondary metabolites. miRNAs are magical, tiny, non-coding ribonucleotides that function as critical regulators of gene expression in eukaryotes. Despite the accumulated knowledge of the miRNA-mediated regulation of several processes, the involvement of miRNAs in regulating secondary plant product biosynthesis is still poorly understood. Here, we summarize the recent progress made in the area of identification and characterizations of miRNAs involved in regulating the biosynthesis of secondary metabolites in plants and discuss the future perspectives for designing the viable strategies for their targeted manipulation.
机译：植物的次生代谢物，如类黄酮，萜类化合物和生物碱等，因其在防御各种植物害虫中的作用以及对人体的药用价值而闻名。由于这些植物化学物质具有巨大的生物学重要性，因此了解其生物合成途径的调控至关重要。近年来，分子技术的进步使我们能够更好地理解与次级代谢产物的生物合成途径有关的蛋白质，酶，基因等。 miRNA是神奇的，微小的非编码核糖核苷酸，可作为真核生物基因表达的关键调节剂。尽管积累了关于miRNA介导的几个过程调控的知识，但对miRNA参与调控植物次生生物合成的调控仍知之甚少。在这里，我们总结了在调控植物次生代谢产物生物合成的miRNA的鉴定和表征领域中取得的最新进展，并讨论了设计针对其靶向操作的可行策略的未来观点。

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