• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>other >Motion of Tympanic Membrane in Guinea Pig Otitis Media Model Measured by Scanning Laser Doppler Vibrometry
【2h】

Motion of Tympanic Membrane in Guinea Pig Otitis Media Model Measured by Scanning Laser Doppler Vibrometry

机译：扫描激光多普勒振动法测量豚鼠中耳炎模型中鼓膜的运动。

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Otitis media (OM) is an inflammatory or infectious disease of the middle ear. Acute otitis media (AOM) and otitis media with effusion (OME) are the two major types of OM. However, the tympanic membrane (TM) motion differences induced by AOM and OME have not been quantified in animal models in the literature. In this study, the guinea pig AOM and OME models were created by transbullar injection of Streptococcus pneumoniae type 3 and lipopolysaccharide, respectively. To explore the effects of OM on the entire TM vibration, the measurements of full-field TM motions were performed in the AOM, OME and untreated control ears by using scanning laser Doppler vibrometry (SLDV). The results showed that both AOM and OME generally reduced the displacement peak and produced the traveling-wave-like motions at relatively low frequencies. Compared with the normal ear, OME resulted in a significant change of the TM displacement mainly in the inferior portion of the TM, and AOM significantly affected the surface motion across four quadrants. The SLDV measurements provide more insight into sound-induced TM vibration in diseased ears.
机译：中耳炎（OM）是中耳的炎症或感染性疾病。急性中耳炎（AOM）和渗出性中耳炎（OME）是OM的两种主要类型。但是，由AOM和OME引起的鼓膜（TM）运动差异尚未在文献中的动物模型中量化。在这项研究中，豚鼠的AOM和OME模型是分别通过经球茎注射3型肺炎链球菌和脂多糖而建立的。为了探索OM对整个TM振动的影响，使用扫描激光多普勒振动法（SLDV）在AOM，OME和未经处理的对照耳中进行了全场TM运动的测量。结果表明，AOM和OME通常都减小了位移峰值，并在相对较低的频率下产生了行波状运动。与正常耳朵相比，OME导致TM位移的显着变化，主要发生在TM的下部，而AOM显着影响了四个象限的表面运动。 SLDV测量可以更深入地了解患病耳朵中声音引起的TM振动。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号