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Low-level laser therapy/photobiomodulation in the management of side effects of chemoradiation therapy in head and neck cancer: part 2: proposed applications and treatment protocols

机译:在头颈癌化学放射治疗的副作用管理中的低水平激光治疗/光生物调节:第2部分:建议的应用和治疗方案

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摘要

PurposeThere is a large body of evidence supporting the efficacy of low-level laser therapy (LLLT), more recently termed photobiomodulation (PBM) for the management of oral mucositis (OM) in patients undergoing radiotherapy for head and neck cancer (HNC). Recent advances in PBM technology, together with a better understanding of mechanisms involved and dosimetric parameters may lead to the management of a broader range of complications associated with HNC treatment. This could enhance patient adherence to cancer therapy, and improve quality of life and treatment outcomes. The mechanisms of action, dosimetric, and safety considerations for PBM have been reviewed in part 1. Part 2 discusses the head and neck treatment side effects for which PBM may prove to be effective. In addition, PBM parameters for each of these complications are suggested and future research directions are discussed.
机译:目的有大量证据支持低水平激光治疗(LLLT)的功效,最近将其称为光生物调节(PBM)用于接受头颈癌(HNC)放射治疗的患者的口腔粘膜炎(OM)的管理。 PBM技术的最新进展,加上对所涉及机制和剂量学参数的更深入了解,可能会导致管理与HNC治疗相关的各种并发症。这可以增强患者对癌症治疗的依从性,并改善生活质量和治疗结果。第1部分已经回顾了PBM的作用机理,剂量学和安全性考虑。第2部分讨论了PBM可能被证明有效的头部和颈部治疗副作用。此外,针对每种并发症的PBM参数均已提出,并讨论了未来的研究方向。

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