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RECENT DEVELOPMENTS IN ELECTROCHEMICAL SENSORS FOR THE DETECTION OF NEUROTRANSMITTERS FOR APPLICATIONS IN BIOMEDICINE

机译:电化学传感器在生物医学中的应用研究进展

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摘要

Neurotransmitters are important biological molecules that are essential to many neurophysiological processes including memory, cognition, and behavioral states. The development of analytical methodologies to accurately detect neurotransmitters is of great importance in neurological and biological research. Specifically designed microelectrodes or microbiosensors have demonstrated potential for rapid, real-time measurements with high spatial resolution. Such devices can facilitate study of the role and mechanism of action of neurotransmitters and can find potential uses in biomedicine. This paper reviews the current status and recent advances in the development and application of electrochemical sensors for the detection of small-molecule neurotransmitters. Measurement challenges and opportunities of electroanalytical methods to advance study and understanding of neurotransmitters in various biological models and disease conditions are discussed.
机译:神经递质是重要的生物分子,对于许多神经生理过程(包括记忆,认知和行为状态)必不可少。准确检测神经递质的分析方法的发展在神经和生物学研究中非常重要。经过专门设计的微电极或微生物传感器已证明具有以高空间分辨率进行快速,实时测量的潜力。这样的装置可以促进对神经递质的作用和作用机理的研究,并可以发现其在生物医学中的潜在用途。本文综述了用于检测小分子神经递质的电化学传感器的研究现状和最新进展。讨论了电分析方法的测量挑战和机遇,以促进在各种生物学模型和疾病条件下对神经递质的研究和理解。

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