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首页> 美国卫生研究院文献>other >Feasibility of a Novel Functional Sensibility Test as an Assisted Examination for Determining Precision Pinch Performance in Patients with Carpal Tunnel Syndrome
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Feasibility of a Novel Functional Sensibility Test as an Assisted Examination for Determining Precision Pinch Performance in Patients with Carpal Tunnel Syndrome

机译：新型功能敏感性试验作为辅助检查以确定腕管综合征患者的精确捏性能的可行性

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To understand the feasibility of a novel functional sensibility test for determining precision pinch performance in patients with carpal tunnel syndrome, this study investigates the validity, sensitivity and specificity of functional sensibility derived from a pinch-holding-up activity (PHUA) test. Participants include 70 clinically defined carpal tunnel syndrome (CTS) patients with 119 involved hands and 70 age- and gender-matched controls. To examine the discriminating ability of the functional sensibility test, the differences in the ability of pinch force adjustments to the inertial load of handling object between CTS and control subjects are analyzed. The results of functional sensibility are correlated with the severity of CTS to establish concurrent validity. The receiver operating characteristic (ROC) curve is constructed to demonstrate the accuracy of the proposed test. The functional sensibility score significantly discriminates the patients and control groups (respectively, 12.94±1.72 vs. 11.51±1.15N in peak pinch force (FPPeak), p<0.001; 2.92±0.41 vs. 2.52±0.24 in force ratio, p<0.001) and is moderately correlated (r = 0.42–0.54, p<0.001) with the results of traditional sensibility tests (touch-pressure threshold and two-point discrimination test). In addition, there is a statistical difference in the results of functional sensibility (p<0.001) among the subgroups of CTS severity based on electrophysiological study. The sensitivity and specificity are 0.79 and 0.76, respectively, for the functional sensibility test. The areas under the ROC curve are 0.85 and 0.80 for the force ratio and FPPeak, respectively. In conclusion, the functional sensibility test could be feasibly used as a clinical tool for determining both the sensibility and precision pinch performance of hands for the patients with CTS.
机译：为了了解一种新的功能敏感性测试在腕管综合征患者中确定精确捏性能的可行性，本研究调查了从捏捏保持活动（PHUA）测试得出的功能敏感性的有效性，敏感性和特异性。参加者包括70例临床定义的腕管综合症（CTS）患者，其中119例涉及双手，另外70例年龄和性别相匹配。为了检验功能敏感性测试的区分能力，分析了CTS和控制对象之间对操作对象的惯性负载进行捏力调整的能力的差异。功能敏感性的结果与CTS的严重程度相关，以建立并发有效性。构造接收器工作特性（ROC）曲线以证明所提出测试的准确性。功能敏感性评分可明显区分患者和对照组（分别为12.94±1.72 vs.11.51±1.15N峰值捏合力（FPPeak），p <0.001; 2.92±0.41 vs.2.52±0.24的受力比例，p <0.001 ），并且与传统敏感性测试（触摸压力阈值和两点鉴别测试）的结果具有中等相关性（r = 0.42-0.54，p <0.001）。此外，根据电生理研究，CTS严重程度亚组之间的功能敏感性结果之间存在统计学差异（p <0.001）。功能敏感性测试的敏感性和特异性分别为0.79和0.76。对于力比和FPPeak，ROC曲线下的面积分别为0.85和0.80。总之，功能敏感性测试可作为确定CTS患者手的敏感性和精确捏捏性能的临床工具而可行。

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