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TransRadial Education And Therapeutics (TREAT): Shifting the balance of safety and efficacy of antithrombotic agents in percutaneous coronary intervention. A report from the Cardiac Safety Research Consortium

机译:经桡动脉教育和治疗(治疗):转移的安全性和抗血栓药物疗效的平衡经皮冠状动脉介入。从心脏安全研究协会的报告

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摘要

Percutaneous coronary intervention (PCI) is an integral part of the treatment of coronary artery disease. The most common complication of PCI, bleeding, typically occurs at the vascular access site and is associated with short-term and long-term morbidity and mortality. Periprocedural bleeding also represents the primary safety concern of concomitant antithrombotic therapies essential for PCI success. Use of radial access for PCI reduces procedural bleeding and hence may change the risk profile and net clinical benefit of these drugs. This new drug-device safety interaction creates opportunities to advance the safe and effective use of antithrombotic agents during PCI. In June 2010 and March 2011, leaders from government, academia, professional societies, device manufacturing, and pharmaceutical industries convened for 2 think tank meetings. Titled TREAT I and II, these forums examined approaches to improve the overall safety of PCI by optimizing strategies for antithrombotic drug use and radial artery access. This article summarizes the content and proceedings of these sessions.
机译:经皮冠状动脉介入治疗(PCI)是冠状动脉疾病治疗不可或缺的一部分。 PCI的最常见并发症是出血,通常发生在血管通路部位,并与短期和长期发病率和死亡率相关。围手术期出血也代表了PCI成功所必需的同时进行抗栓治疗的主要安全问题。 radial动脉入路用于PCI可以减少程序性出血,因此可以改变这些药物的风险状况和临床净收益。这种新的药物设备安全性相互作用为在PCI期间安全有效地使用抗血栓形成药创造了机会。 2010年6月和2011年3月,来自政府,学术界,专业协会,设备制造和制药行业的领导人召集了两次智囊团会议。这些论坛的标题为TREAT I和II,探讨了通过优化抗血栓药物使用和radial动脉通路的策略来提高PCI整体安全性的方法。本文总结了这些会议的内容和会议记录。

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