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Impact of the Mycobaterium africanum West Africa 2 Lineage on TB Diagnostics in West Africa: Decreased Sensitivity of Rapid Identification Tests in The Gambia

机译:非洲分枝杆菌非洲西部2谱系对西非结核病诊断的影响:冈比亚快速鉴定测试的敏感性降低

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摘要

BackgroundMPT64 rapid speciation tests are increasingly being used in diagnosis of tuberculosis (TB). Mycobacterium africanum West Africa 2 (Maf 2) remains an important cause of TB in West Africa and causes one third of disease in The Gambia. Since the introduction of MPT64 antigen tests, a higher than expected rate of suspected non-tuberculous mycobacteria (NTM) was seen among AFB smear positive TB suspects, which led us to prospectively assess sensitivity of the MPT64 antigen test in our setting.
机译:背景技术MPT64快速形态分析测试越来越多地用于诊断结核病(TB)。非洲分枝杆菌西非2(Maf 2)仍然是西非结核的重要病因,在冈比亚造成三分之一的疾病。自从引入MPT64抗原检测以来,AFB涂片阳性结核病嫌疑人中发现的非结核分枝杆菌(NTM)疑似病例的发生率高于预期,这使我们能够前瞻性地评估MPT64抗原检测的敏感性。

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