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首页> 美国卫生研究院文献>Bosnian Journal of Basic Medical Sciences >MEAN OF CA 125 IN MAKING THERAPY DECISION IN ADNEXAL INFLAMMATORY TUMORS
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MEAN OF CA 125 IN MAKING THERAPY DECISION IN ADNEXAL INFLAMMATORY TUMORS

机译：CA 125决定附件炎性肿瘤的治疗方案

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摘要

Laboratory findings such are white blood count and sedimentation rate are of relative value in inflammations of the upper genital tract and adnexal inflammatory tumors. Antibiotics are administrated in all cases according to the protocol but some of them need operative treatment also. Inflammatory tumors can develope in endometriotic and even in cancer adnexal masses. CA 125 is elevated in great number of patients with advanced ovarian cancer. It can also be elevated in endometriosis, inflammations and in nongynecological malignacies. Adnexal inflammatory tumor was confirmed in 57 patients. Laboratory findings: white blood count and sedimentation rate were in normal levels in 17 patients. CA 125 was elevated in 27 patients. 49 patients were operated and CA 125 decreased in the first 5 days after the operation. Only 8 patients without CA 125 elevation were sucessfully treated by mean of antibiotics. Even there is no need for routine examining of serum CA 125 in adnexal inflammatory tumors it can be examined in cases with suspected Doppler ultrasonographic findings or unclear clinical findings. Endometriosis brings some risk of malignancy. Inflammatory tumor can develop in endometriotic tumor as well as in necrotic malignant ovary tissue. These could be reasons for making decision to do the operation in cases with inflammatory tumor followed with increased CA 125, hystological assesment and serious interpretation of final results.
机译：实验室检查结果如白血球计数和沉降速率在上生殖道炎症和附件炎性肿瘤中具有相对价值。根据协议，在所有情况下都使用抗生素，但其中一些也需要进行手术治疗。炎症性肿瘤可在内膜异位症甚至癌症附件肿块中发展。在许多晚期卵巢癌患者中，CA 125升高。在子宫内膜异位症，炎症和非妇科恶性肿瘤中也可能升高。在57例患者中确认了肾上腺炎性肿瘤。实验室检查结果：17例患者的白血球计数和沉降率均处于正常水平。 27名患者的CA 125升高。手术49例，术后第5天CA 125下降。仅8例无CA 125升高的患者通过抗生素成功治疗。即使不需要常规检查附件炎性肿瘤中的血清CA 125，也可以在怀疑有多普勒超声检查发现或临床结果不清楚的情况下进行检查。子宫内膜异位会带来恶性肿瘤的风险。炎性肿瘤可在子宫内膜异位肿瘤以及坏死的卵巢组织中发展。这些可能是决定在炎症性肿瘤，CA 125升高，体格检查和对最终结果的认真解释之后决定进行手术的原因。

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