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Defects in the cytoplasmic assembly of axonemal dynein arms cause morphological abnormalities and dysmotility in sperm cells leading to male infertility

机译：Axonemal Dynein Arms的细胞质组装中的缺陷会导致精子细胞的形态异常和功能性导致男性不孕症

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期刊名称 PLoS Genetics
作者
Isabella Aprea; Johanna Raidt; Inga Marlena Höben; Niki Tomas Loges; Tabea Nöthe-Menchen; Petra Pennekamp; Heike Olbrich; Thomas Kaiser; Luisa Biebach; Frank Tüttelmann; Judit Horvath; Maria Schubert; Claudia Krallmann; Sabine Kliesch; Heymut Omran;
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年(卷),期 2021(17),2
年度 2021
页码 e1009306
总页数 33
原文格式 PDF
正文语种
中图分类遗传学;
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专利

1. Mutations in DNAH1, which encodes an inner arm heavy chain dynein, lead to male infertility from multiple morphological abnormalities of the sperm flagella [J] . BenKhelifaM., CouttonC., ZouariR., The American Journal of Human Genetics . 2014,第1期

机译：DNAH1突变，编码一条内臂重链动力蛋白，导致精子鞭毛的多种形态异常导致男性不育
2. Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia [J] . Whitfield Marjorie, Thomas Lucie, Bequignon Emilie, The American Journal of Human Genetics . 2019,第1期

机译：DNAH17中的突变，编码特异性特异性的Axonemal外部Dynein Arm重链，导致由于哮喘患者引起孤立的男性不孕症
3. Chlamydomonas Axonemal Dynein Assembly Locus ODA8 Encodes a Conserved Flagellar Protein Needed for Cytoplasmic Maturation of Outer Dynein Arm Complexes [J] . Desai Paurav B., Freshour Judy R., Mitchell David R. Cytoskeleton . 2015,第1期

机译：衣藻轴索动力蛋白装配位点ODA8编码保守的鞭毛蛋白，需要外部动力蛋白胞质成熟。
4. Mutations in DNAH1 which Encodes an Inner Arm Heavy Chain Dynein Lead to Male Infertility from Multiple Morphological Abnormalities of the Sperm Flagella [O] . Mariem Ben Khelifa, Charles Coutton, Raoudha Zouari, 2014

机译：DNAH1的突变其编码一条手臂的重链动力蛋白导致精子鞭毛的多种形态异常导致男性不育
5. Defects in the cytoplasmic assembly of axonemal dynein arms cause morphological abnormalities and dysmotility in sperm cells leading to male infertility [O] . Isabella Aprea, Johanna Raidt, Inga Marlena Höben, 2021

机译：Axonemal Dynein Arms的细胞质组装中的缺陷会导致精子细胞的形态异常和功能性导致男性不孕症

Defects in the cytoplasmic assembly of axonemal dynein arms cause morphological abnormalities and dysmotility in sperm cells leading to male infertility

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