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Development of a methodology to make individual estimates of the precision of liquid chromatography-tandem mass spectrometry drug assay results for use in population pharmacokinetic modeling and the optimization of dosage regimens

机译：制定方法使液相色谱 - 串联质谱药物测定的精度估计用于群体药代动力学建模和剂量方案的优化

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期刊名称 PLoS ONE
作者
Gellért Balázs Karvaly; Michael N. Neely; Krisztián Kovács; István Vincze; Barna Vásárhelyi; Roger W. Jelliffe; Jed N. Lampe; Jed N. Lampe; Jed N. Lampe;
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作者单位

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年(卷),期 2020(15),3
年度 2020
页码 e0229873
总页数 22
原文格式 PDF
正文语种
中图分类生物学;
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1. Development of a methodology to make individual estimates of the precision of liquid chromatography-tandem mass spectrometry drug assay results for use in population pharmacokinetic modeling and the optimization of dosage regimens [J] . Gellért Balázs Karvaly, Michael N. Neely, Krisztián Kovács, PLoS One . 2020,第3期

机译：制定方法，使液相色谱 - 串联质谱药物测定的精度估计用于群体药代动力学建模和剂量方案的优化
2. Use of an intravenous microdose of 14C-labeled drug and accelerator mass spectrometry to measure absolute oral bioavailability in dogs; cross-comparison of assay methods by accelerator mass spectrometry and liquid chromatography-tandem mass spectrometry. [J] . Miyaji Y, Ishizuka T, Kawai K, Drug metabolism and pharmacokinetics. . 2009,第2期

机译：使用14C标记药物的静脉内微量剂量和促进剂质谱法测量狗的绝对口服生物利用度;通过加速器质谱和液相色谱-串联质谱法对测定方法进行交叉比较。
3. Use of an intravenous microdose of 14C-labeled drug and accelerator mass spectrometry to measure absolute oral bioavailability in dogs; cross-comparison of assay methods by accelerator mass spectrometry and liquid chromatography-tandem mass spectrometry. [J] . Miyaji Y, Ishizuka T, Kawai K, Drug metabolism and pharmacokinetics. . 2009,第2期

机译：使用14C标记药物的静脉内微量剂量和促进剂质谱法测量狗的绝对口服生物利用度;通过加速器质谱和液相色谱-串联质谱法对测定方法进行交叉比较。
4. Development and Validation of a Quantitative Assay for the Measurement of Desmopressin in Rat Plasma by Liquid Chromatography-Tandem Mass Spectrometry [C] . YUN CHEN, Toni Jean Thompson ASMS Conference on Mass Spectrometry and Allied Topics . 2008

机译：通过液相色谱 - 串联质谱法测定大鼠等离子体中去膜素的定量测定的显影和验证
5. Methodologies for emerging contaminants in environmental and food matrices by liquid chromatography-tandem mass spectrometry and by capillary electrophoresis-inductively coupled plamsa-mass spectrometry. [D] . Tso, Jerry. 2011

机译：通过液相色谱-串联质谱法和毛细管电泳-电感耦合偶数质谱法对环境和食品基质中新出现的污染物进行分析的方法。
6. Development of a robust sensitive and selective liquid chromatography-tandem mass spectrometry assay for the quantification of the novel macrocyclic peptide kappa opioid receptor antagonist D-TrpCJ-15208 in plasma and application to an initial pharmacokinetic study [O] . Tanvir Khaliq, Todd D. Williams, Sanjeewa N. Senadheera, -1

机译：鲁棒性灵敏性和选择性液相色谱-串联质谱分析方法的开发用于定量测定血浆中新型大环肽κ阿片受体拮抗剂D-Trp CJ-15208及其在初始药代动力学研究中的应用
7. Development of a robust, sensitive and selective liquid chromatography-tandem mass spectrometry assay for the quantification of the novel macrocyclic peptide kappa opioid receptor antagonist [D-Trp]CJ-15,208 in plasma and application to an initial pharmacokinetic study [O] . Department of Medicinal Chemistry, the University of Kansas, Lawrence, KS 66045, USA ( host institution ), Khaliq, Tanvir ( UF author ), Williams, Todd D. ( author ), 2016

机译：鲁棒性，灵敏性和选择性液相色谱-串联质谱分析方法的开发，用于定量测定血浆中新型大环肽κ阿片受体拮抗剂[D-Trp] CJ-15,208及其在初始药代动力学研究中的应用

Development of a methodology to make individual estimates of the precision of liquid chromatography-tandem mass spectrometry drug assay results for use in population pharmacokinetic modeling and the optimization of dosage regimens

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