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首页> 美国卫生研究院文献>ISRN Obesity >Associations of Body Mass Index (Maternal BMI) and Gestational Diabetes Mellitus with Neonatal and Maternal Pregnancy Outcomes in a Multicentre European Database (Diabetes and Pregnancy Vitamin D and Lifestyle Intervention for Gestational Diabetes Mellitus Prevention)
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Associations of Body Mass Index (Maternal BMI) and Gestational Diabetes Mellitus with Neonatal and Maternal Pregnancy Outcomes in a Multicentre European Database (Diabetes and Pregnancy Vitamin D and Lifestyle Intervention for Gestational Diabetes Mellitus Prevention)

机译：欧洲多中心数据库中的体重指数（孕妇BMI）和妊娠糖尿病与新生儿和孕妇妊娠结局的关系（糖尿病和妊娠维生素D以及生活方式干预对预防妊娠糖尿病的影响）

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Objective. Assess the impact of Gestational Diabetes Mellitus (GDM) and obesity on neonatal and maternal pregnancy outcomes. Methods. Cross-sectional data (3343 pregnancies) from seven European centres were included in a multilevel analysis of the association between GDM/obesity and caesarean section, macrosomia and neonatal morbidities. Results. Comparison of databases identified reporting differences between countries due to the inclusion of true population based samples or pregnancies from specialised tertiary centres, resulting in higher prevalences of GDM for some countries. The analysis showed that obesity and GDM were independent risk factors of perinatal complications. Only BMI had a dose-dependent effect on the risk of macrosomia and caesarean section. Both obesity (BMI > 30 kg/m2) and GDM were independent risk factors of neonatal morbidities. Conclusions. Obesity and GDM were independent risk factors of perinatal complications. The effect of the worldwide obesity and diabetes epidemic is extending to the next generation.
机译：目的。评估妊娠糖尿病和肥胖对新生儿和孕妇妊娠结局的影响。方法。来自七个欧洲中心的横断面数据（3343例妊娠）包括在GDM /肥胖与剖腹产，巨大儿和新生儿发病率之间的关联的多层次分析中。结果。对数据库的比较发现，由于纳入了基于人口的真实样本或来自专业三级中心的怀孕，导致国家间报告差异，导致某些国家的GDM患病率更高。分析表明，肥胖和GDM是围产期并发症的独立危险因素。只有BMI对巨人症和剖腹产的风险具有剂量依赖性。肥胖（BMI> 30 kg / m 2 ）和GDM都是新生儿发病的独立危险因素。结论。肥胖和GDM是围产期并发症的独立危险因素。全球肥胖和糖尿病流行的影响正在扩展到下一代。

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