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首页> 外文期刊>Acta Pharmacologica Sinica >Recent advances in traditional plant drugs and orchids
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Recent advances in traditional plant drugs and orchids

机译:传统植物药和兰花的最新进展

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The main objective of this paper is to review recent advances in plant drug research and developments in orchid study, in an attempt to provide useful references for plant drug studies. Plants have been used as medicine for millennia. Out of estimated 250 000 to 350 000 plant species identified so far, about 35 000 are used worldwide for medicinal purposes. It has been confirmed by WHO that herbal medicines serve the health needs of about 80 percent of the world's population; especially for millions of people in the vast rural areas of developing countries. Meanwhile, consumers in developed countries are becoming disillusioned with modern healthcare and are seeking alternatives. The recent resurgence of plant remedies results from several factors: 1) the effectiveness of plant medicines; 2) the side effect of most modern drugs; and 3) the development of science and technology. It has been estimated that in the mid-1990s over 200 companies and research organizations worldwide are screening plant and animal compounds for medicinal properties. Actually, several important drugs used in modern medicine have come from medicinal plant studies, eg, taxol/paclitaxel, vinblastine, vincristine, topotecan, irinotecan, etoposide, teniposide, etc. As for drugs derived from orchids, some novel discoveries, both in phytochemical and pharmacological properties, were reported by some universities. However, studies on plants are very limited. Only about a third of the million or so species of higher plants have been identified and named by scientists. Of those named, only a tiny fraction has been studied. Nowadays the linking of the indigenous knowledge of medicinal plants to modern research activities provides a new approach, which makes the rate of discovery of drugs much more effective than with random collection.
机译:本文的主要目的是回顾植物药物研究的最新进展以及兰花研究的发展,以期为植物药物研究提供有用的参考。几千年来,植物一直被用作药物。到目前为止,在估计的25万至35万种植物中,全世界约有3.5万种用于医学目的。世卫组织已经证实,草药满足了世界约80%人口的健康需求;特别是针对发展中国家广大农村地区的数百万人。同时,发达国家的消费者对现代医疗保健已开始幻灭,并正在寻求替代方案。最近植物疗法的兴起源于以下几个因素:1)植物药的有效性; 2)大多数现代药物的副作用; (三)科学技术发展。据估计,在1990年代中期,全世界有200多家公司和研究组织正在筛选植物和动物化合物的药用特性。实际上,现代医学中使用的几种重要药物都来自药用植物研究,例如紫杉醇/紫杉醇,长春碱,长春新碱,托泊替康,伊立替康,依托泊苷,替尼泊苷等。一些大学报告了其药理特性。但是,对植物的研究非常有限。科学家仅识别和命名了大约一百万种高等植物物种中的三分之一。在那些名字中,只有很小一部分被研究过。如今,将药用植物的本土知识与现代研究活动联系起来,提供了一种新方法,这使得药物的发现率比随机收集更为有效。

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