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Achieving Immortality

机译:实现永生

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Avoiding death has been a popular goal throughout the ages, and anti-aging elixirs have never been in short supply. Although the best shot at immortality is still through one's work, there is hope on the scientific horizon that people may be able to live considerably longer than they do now. Over the past 15 years or so, the implementation of molecular genetic approaches in a number of different laboratory organisms has revolutionized research on aging. By systematically manipulating the genes of worms, flies and yeast cells, investigators have identified dozens of genes that can extend the normal life span of each of these species. And the mammalian counterparts of some of those genes seem to share those same life-extending properties-at least in mice. So, the good news is that life span is a plastic trait and that we have identified a large number of genes that can act to delay the aging process. The bad news is that we know next to nothing of how these genes influence life span.
机译:避免死亡一直是各个年龄段的普遍目标,而抗衰老长寿药从未短缺。尽管长生不老的最好方法仍然是人们的工作,但从科学的角度来看,人们希望人们的寿命可能比现在更长。在过去的15年左右的时间里,在许多不同的实验室生物中实施分子遗传学方法彻底改变了衰老研究。通过系统地操纵蠕虫,果蝇和酵母细胞的基因,研究人员已经鉴定出数十种基因,可以延长每种物种的正常寿命。而且其中某些基因的哺乳动物对应物似乎具有相同的寿命延长特性,至少在小鼠中是如此。因此,好消息是寿命是可塑性,我们已经鉴定出大量可延缓衰老过程的基因。坏消息是,我们几乎不了解这些基因如何影响寿命。

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