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首页> 外文期刊>Animal Science Journal >Evaluation of the heat-killed and dried cell preparation of Enterococcus faecalis against villous atrophy in early-weaned mice and pigs
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Evaluation of the heat-killed and dried cell preparation of Enterococcus faecalis against villous atrophy in early-weaned mice and pigs

机译：粪肠球菌的热杀死和干细胞制剂对断奶的小鼠和猪的绒毛萎缩的评估

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摘要

Early weaning induces villous atrophy in the small intestine (SI) of piglets. Oral administration of live lactic acid bacteria (LAB) can improve villous shortening. In this study, we evaluated the oral administration of a heat-killed and dried cell preparation of Enterococcus faecalis (a LAB) strain EC-12 against villous atrophy in early-weaned mice (Experiment 1) and pigs (Experiments 2 and 3). Twelve 16-days-old mice were divided into two groups in Experiment 1: gavage of EC-12 (10?mg/kg body weight (BW)/day), or control. On day 21, SI was collected. Eighteen 21-day-old pigs were divided into two groups in Experiment 2: gavage of EC-12 (10?mg/kg BW/day), or control. After 10?days, the villous height of jejunum was measured. Six 21-day-old pigs were divided into two groups in Experiment 3: the basal diet supplemented with EC-12 at 0.05%-fed group, or the basal diet-fed group. After 10?days, the villous height of jejunum was measured. The villous heights in SI were significantly higher by EC-12 administration in all experiments. EC-12 successfully improved the villous atrophy in the early-weaned mice and pigs when EC-12 was administered orally.
机译：早期断奶在仔猪的小肠（SI）中引起绒毛萎缩。口服活乳酸菌（LAB）可以改善绒毛缩短。在这项研究中，我们评估了对早期断奶的小鼠（实验1）和猪（实验2和3）中粪肠球菌（LAB）EC-12的热灭活和干燥细胞制剂对绒毛萎缩的口服给药。在实验1中将12只16天大的小鼠分为两组：管饲EC-12（10？mg / kg体重（BW）/天）或对照组。在第21天，收集SI。在实验2中，将18只21天大的猪分为两组：管饲EC-12（10？mg / kg BW /天）或对照组。 10天后，测量空肠的绒毛高度。在实验3中，将6只21天大的猪分为两组：基础日粮中添加了饲喂0.05％饲料的EC-12组或基础日粮组。 10天后，测量空肠的绒毛高度。在所有实验中，通过EC-12给药，SI中的绒毛高度均显着较高。口服EC-12时，EC-12成功改善了早期断奶小鼠和猪的绒毛萎缩。

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