Evaluation of delayed18F-FDG PET in differential diagnosis for malignant soft-tissue tumors

Keisuke Enomoto; Ichiro Higuchi; Jun Hatazawa; Kenichiro Hamada; Yasuhiko Tomita; Takafumi Ueda; Shigeki Kakunaga; Akira Myoui; Hideki Yoshikawa

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Evaluation of delayed18F-FDG PET in differential diagnosis for malignant soft-tissue tumors

机译：延迟18 F-FDG PET在恶性软组织肿瘤鉴别诊断中的价值

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Positron emission tomography (PET) with 2-deoxy-2-[18F]fiuoro-D-glucose (18F-FDG) has been used for the evaluation of soft-tissue tumors. However, the range of accumulation of18F-FDG for malignant soft-tissue lesions overlaps with that of benign lesions. The aim of this study is to investigate the usefulness of delayed18F-FDG PET imaging in the differentiation between malignant and benign soft-tissue tumors.

机译：用2-脱氧-2- [18 F]氟-D-葡萄糖（18 F-FDG）进行正电子发射断层扫描（PET）用于软组织肿瘤的评估。然而，18 F-FDG在恶性软组织病变中的累积范围与良性病变重叠。这项研究的目的是探讨延迟18 F-FDG PET显像在区分恶性和良性软组织肿瘤中的作用。

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来源
《Annals of Nuclear Medicine》 |2006年第10期|671-675|共5页
作者
Keisuke Enomoto; Ichiro Higuchi; Jun Hatazawa; Kenichiro Hamada; Yasuhiko Tomita; Takafumi Ueda; Shigeki Kakunaga; Akira Myoui; Hideki Yoshikawa;
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作者单位

Department of Nuclear Medicine and Tracer Kinetics Osaka University Graduate School of Medicine 2-2 Yamadaoka 565-0871 Suita Osaka JAPAN;

Department of Nuclear Medicine and Tracer Kinetics Osaka University Graduate School of Medicine 2-2 Yamadaoka 565-0871 Suita Osaka JAPAN;

Department of Nuclear Medicine and Tracer Kinetics Osaka University Graduate School of Medicine 2-2 Yamadaoka 565-0871 Suita Osaka JAPAN;

Department of Nuclear Medicine and Tracer Kinetics Osaka University Graduate School of Medicine 2-2 Yamadaoka 565-0871 Suita Osaka JAPAN;

Departments of Pathology Osaka University Graduate School of Medicine JAPAN;

Departments of Orthopaedics Osaka University Graduate School of Medicine 2-2 Yamadaoka 565-0871 Suita Osaka JAPAN;

Departments of Orthopaedics Osaka University Graduate School of Medicine 2-2 Yamadaoka 565-0871 Suita Osaka JAPAN;

Departments of Orthopaedics Osaka University Graduate School of Medicine 2-2 Yamadaoka 565-0871 Suita Osaka JAPAN;

Departments of Orthopaedics Osaka University Graduate School of Medicine 2-2 Yamadaoka 565-0871 Suita Osaka JAPAN;

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正文语种 eng
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positron emission tomography; soft-tissue tumor; 2-deoxy-2-18Ffluoro-D-glucose;

机译：正电子发射断层扫描;软组织肿瘤;2-脱氧-2- [18F]氟-D-葡萄糖;

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1. Comparison of ~(11)C-choline PET and FDG PET for the differential diagnosis of malignant tumors [J] . European Journal of Nuclear Medicine Group European journal of nuclear medicine . 2004,第8期

机译：〜（11）C-胆碱PET与FDG PET鉴别诊断恶性肿瘤的比较
2. Differential Diagnosis of Borderline Ovarian Tumors from Stage I Malignant Ovarian Tumors using FDG PET/CT [J] . Chulhan Kim, Hyun Hoon Chung, So Won Oh, Nuclear Medicine and Molecular Imaging . 2013,第2期

机译：应用FDG PET / CT鉴别诊断I期恶性卵巢肿瘤与交界性卵巢肿瘤
3. The use of 18F-FDG PET ratios in the differential diagnosis of common malignant brain tumors [J] . Meric Kaan, Killeen Ronan P., Abi-Ghanem Alain S., Clinical imaging . 2015,第6期

机译：使用18F-FDG宠物比在常见恶性脑肿瘤的鉴别诊断中
4. Spectropolarimetry in the differential diagnosis of benign and malignant ovarian tumors [C] . O.P. Peresunko, S.B. Yermolenko, I. Gruia International conference on correlation optics . 2017

机译：分光光度法在卵巢良恶性肿瘤鉴别诊断中的作用
5. Evaluation of the Role of Tumor-Associated Macrophages in Malignant Melanoma. [D] . Meeth, Katrina M. 2016

机译：评估肿瘤相关巨噬细胞在恶性黑色素瘤中的作用。
6. Differential Diagnosis of Borderline Ovarian Tumors from Stage I Malignant Ovarian Tumors using FDG PET/CT [O] . Chulhan Kim, Hyun Hoon Chung, So Won Oh, 2013

机译：应用FDG PET / CT鉴别诊断I期恶性卵巢肿瘤与交界性卵巢肿瘤
7. Aim: To investigate the value of ElastPQ measurement for differential diagnosis of benign and malignant focal liver lesions (FLLs) by using histologic results as a reference standard. Material and methods: A total of 154 patients were included. ElastPQ measurement was performed for each lesion in which the shear wave speed (SWS) was measured. The difference in SWS and SWS ratio of FLL to surrounding liver were evaluated, and the cut off value was investigated. Receiver operating characteristic (ROC) curve was plotted to evaluate the diagnostic performance. Histology as a gold standard was obtained by surgery in all patients. Results: A total of 154 lesions including 129 (83.7 ) malignant FLLs and 25 (16.3 ) benign ones were analysed. The SWS of malignant and benign FLLs was significantly different, 2.77±0.68 m/s and 1.57±0.55 m/s (p<0.05). The SWS ratio of each FLL to surrounding liver parenchyma was 2.23±0.49 for malignant and 1.14±0.36 for benign FLLs (p<0.05). The cut off value for differential diagnosis was 2.06 m/s for SWS and 1.67 for SWS ratio. Conclusions: ElastPQ measurement provides reliable quantitative stiffness information of FLLs and may be helpful in the differential diagnosis between malignant and benign FLLs. [O] . Yi Dong, Wen-Ping Wang, Yadan Xu, 2017

机译：目的：通过使用组织学结果作为参考标准，研究ELASTPQ测量对良性和恶性局灶性肝病变（FLLS）的鉴别诊断的价值。材料和方法：共有154名患者。对测量剪切波速度（SWS）的每个病变进行ELASTPQ测量。评估了FL1与周围肝脏的SWS和SWS比的差异，研究了切断值。接收器操作特征（ROC）曲线被绘制以评估诊断性能。组织学作为金标准通过患者的手术获得。结果：共有154例病变，包括129名（83.7％）恶性FLLS和25（16.3％）良性物质。 SWS的恶性和良性FLLS显着差异，2.77±0.68 m / s和1.57±0.55 m / s（p <0.05）。对于良性FLL的恶性为2.23±0.36，每个FL1与周围肝实质的SWS比为2.23±0.36（P <0.05）。差分诊断的切断值为SWS和SWS比率为2.06米/秒。结论：ELASTPQ测量提供了FLLS的可靠定量刚度信息，可能有助于恶性和良性FLL之间的差异诊断。

Evaluation of delayed18F-FDG PET in differential diagnosis for malignant soft-tissue tumors

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