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首页> 外文期刊>Applied Physics >Photodisruption of a thin membrane near a solid boundary: an in vitro study of laser capsulotomy
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Photodisruption of a thin membrane near a solid boundary: an in vitro study of laser capsulotomy

机译：固体边界附近薄膜的光致破裂：激光囊切开术的体外研究

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摘要

A Nd:YAG laser photodisruption is a well-established tool for intraocular surgery, such as treatment of posterior capsule opacification that affects the visual function. During the intraocular procedure, called laser capsulotomy, the excitation pulse is focused several times just behind the posterior capsule and intraocular lens to create the central opening in the opacified capsule. We built an in vitro experiment to (1) clarify the influence of the distance between the intraocular lens and the posterior capsule on the total pulse energy required for the capsulotomy, and (2) investigate the main mechanisms responsible for the posterior capsule opening. In our in vitro model, different distances between the solid boundary (imitating an intraocular lens) and the membrane (imitating the posterior capsule) simulate different types of posterior capsule opacification. Our results show that procedure efficiency decreases by decreasing distance between the lens and the capsule. We also explain that for smaller distances between the pulse focus and the membrane, plasma and shock wave are responsible for the capsule disruption. Here, a risk of collateral damage significantly increases. On contrary, the membrane and the bubble jet disrupt the membrane, when pulse focus is moved away and the risk of intraocular lens damage decreases. However, the membrane disruption is not very effective, if it is placed near the solid boundary that inhibits the membrane jet.
机译：Nd：YAG激光光破裂术是眼内手术的成熟工具，例如治疗后囊混浊影响视觉功能的工具。在称为激光囊切开术的眼内手术过程中，将激发脉冲聚焦在后囊和眼内晶状体后面几次，以在不透明的囊中形成中央开口。我们建立了一个体外实验，以（1）明确人工晶状体与后囊之间的距离对切囊术所需的总脉冲能量的影响，以及（2）研究造成后囊开放的主要机制。在我们的体外模型中，实体边界（模拟人工晶状体）和膜（模拟后囊）之间的不同距离模拟了不同类型的后囊混浊。我们的结果表明，通过减少晶状体和囊之间的距离，手术效率会降低。我们还解释说，对于脉冲焦点和膜之间的较小距离，血浆和冲击波是造成胶囊破裂的原因。在此，附带损害的风险显着增加。相反，当脉冲焦点移开并且眼内晶状体受损的风险降低时，膜和气泡喷射会破坏膜。然而，如果将膜破坏置于抑制膜喷射的固体边界附近，则膜破坏不是非常有效。

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  • 来源
    《Applied Physics》 |2016年第2期|118.1-118.7|共7页
  • 作者

    G. Hawlina; B. Drnovsek-Olup; J. Mozina; P. Gregorcic;

  • 作者单位

    Eye Hospital, University Medical Centre Ljubljana, Grabloviceva 46, 1525 Ljubljana, Slovenia,Faculty of Medicine, University of Ljubljana, Vrazov trg 2, 1104 Ljubljana, Slovenia;

    Eye Hospital, University Medical Centre Ljubljana, Grabloviceva 46, 1525 Ljubljana, Slovenia,Faculty of Medicine, University of Ljubljana, Vrazov trg 2, 1104 Ljubljana, Slovenia;

    Faculty of Mechanical Engineering, University of Ljubljana, Askerceva 6, 1000 Ljubljana, Slovenia;

    Faculty of Mechanical Engineering, University of Ljubljana, Askerceva 6, 1000 Ljubljana, Slovenia;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);
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