Loss of DNA damage checkpoint genes: switch from preferential induction of point mutations to chromosomal damage precedes the transition towards an aggressive cancer type

J. G. Hengstler; H. M. Bolt

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Loss of DNA damage checkpoint genes: switch from preferential induction of point mutations to chromosomal damage precedes the transition towards an aggressive cancer type

机译：DNA损伤检查点基因的丢失：先从点突变的优先诱导转变为染色体损伤，然后才向侵略性癌症类型过渡

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《Archives of Toxicology》 |2008年第6期|341-342|共2页
作者
J. G. Hengstler; H. M. Bolt;
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Institut für Arbeitsphysiologie an der Universität Dortmund Leibniz Research Center for Working Environment and Human Factors (IfADo) Ardeystrasse 67 44139 Dortmund Germany;

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1. Loss of DNA damage checkpoint genes: switch from preferential induction of point mutations to chromosomal damage precedes the transition towards an aggressive cancer type. [J] . Hengstler JG, Bolt HM Archives of Toxicology . 2008,第6期

机译：DNA损伤检查点基因的丢失：先从点突变的优先诱导转变为染色体损伤，然后才向侵略性癌症类型过渡。
2. Loss of DNA damage checkpoint genes: switch from preferential induction of point mutations to chromosomal damage precedes the transition towards an aggressive cancer type. [J] . Hengstler JG, Bolt HM Archives of Toxicology . 2008,第6期

机译：DNA损伤检查点基因的丢失：先从点突变的优先诱导转变为染色体损伤，然后才向侵略性癌症类型过渡。
3. Preferential DNA Damage and Poor Repair Determine ras Gene Mutational Hotspot in Human Cancer. [J] . Feng Z, Hu W, Chen JX, Journal of the National Cancer Institute . 2002,第20期

机译：优先的DNA损伤和修复不良决定了人类癌症中的ras基因突变热点。
4. UV RADIATION, DNA DAMAGE, MUTATIONS AND SKIN CANCER [C] . FRANK R. DE GRUIJL, NATO NATO Advanced Study Institute on Environmental UV Radiation: Impact on Ecosystems and Human Health and Predictive Models . 2006

机译：紫外线辐射，DNA损伤，突变和皮肤癌
5. Mechanism of 3,3'-diindolylmethane-induced cell death in human C33A cervical cancer cells: Induction of endoplasmic reticulum stress, apoptosis and the role of growth-arrest and DNA-damage genes [D] . Han, Jing Y. 2009

机译：3,3'-二吲哚基甲烷诱导的人C33A宫颈癌细胞死亡的机制：内质网应激，细胞凋亡以及生长停滞和DNA损伤基因的作用
6. DNA Damage Repair Gene Mutations Are Indicative of a Favorable Prognosis in Colorectal Cancer Treated With Immune Checkpoint Inhibitors [O] . Yipeng Song, Jian Huang, Dandan Liang, 2020

机译：DNA损伤修复基因突变表明用免疫检查点抑制剂治疗的结肠直肠癌的良好预后
7. DNA Damage Repair Gene Mutations Are Indicative of a Favorable Prognosis in Colorectal Cancer Treated With Immune Checkpoint Inhibitors [O] . Yipeng Song, Jian Huang, Dandan Liang, 2021

机译：DNA损伤修复基因突变表明用免疫检查点抑制剂治疗的结肠直肠癌的良好预后

Loss of DNA damage checkpoint genes: switch from preferential induction of point mutations to chromosomal damage precedes the transition towards an aggressive cancer type

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