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Self-experimentation as a source of new ideas: Ten examples about sleep, mood, health, and weight

机译:自我实验成为新思想的源泉:有关睡眠,情绪,健康和体重的十个例子

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Little is known about how to generate plausible new scientific ideas. So it is noteworthy that 12 years of self-experimentation led to the discovery of several surprising cause-effect relationships and suggested a new theory of weight control, an unusually high rate of new ideas. The cause-effect relationships were: (1) Seeing faces in the morning on television decreased mood in the evening (>10 hrs later) and improved mood the next day (>24 hrs later), yet had no detectable effect before that (0-10 hrs later). The effect was strongest if the faces were life-sized and at a conversational distance. Travel across time zones reduced the effect for a few weeks. (2) Standing 8 hours per day reduced early awakening and made sleep more restorative, even though more standing was associated with less sleep. (3) Morning light (1 hr/day) reduced early awakening and made sleep more restorative. (4) Breakfast increased early awakening. (5) Standing and morning light together eliminated colds (upper respiratory tract infections) for more than 5 years. (6) Drinking lots of water, eating low-glycemic-index foods, and eating sushi each caused a modest weight loss. (7) Drinking unflavored fructose water caused a large weight loss that has lasted more than 1 year. While losing weight, hunger was much less than usual. Unflavored sucrose water had a similar effect. The new theory of weight control, which helped discover this effect, assumes that flavors associated with calories raise the body-fat set point: The stronger the association, the greater the increase. Between meals the set point declines. Self-experimentation lasting months or years seems to be a good way to generate plausible new ideas.
机译:关于如何产生合理的新科学思想知之甚少。因此,值得注意的是,经过12年的自我实验,发现了一些令人惊讶的因果关系,并提出了一种新的体重控制理论,即异常高的新观念。因果关系是:(1)早上在电视上看脸,晚上(> 10小时后)情绪下降,第二天(> 24小时后)情绪改善,但在此之前没有可察觉的影响(0 -10小时后)。如果脸部具有真人大小并且可以对话,那么效果最强。跨时区旅行减少了数周的影响。 (2)每天站立8小时可减少早期醒来,并使睡眠更具恢复性,即使站立更多与睡眠减少有关。 (3)清晨的阳光(每天1小时)减少了早期的清醒,使睡眠更具恢复性。 (4)早餐增加了早醒时间。 (5)站立和晨光共同消除感冒(上呼吸道感染)超过5年。 (6)大量喝水,吃低血糖指数的食物和吃寿司会使体重减轻一些。 (7)喝无味果糖水会导致体重减轻,持续超过1年。在减轻体重的同时,饥饿比平常少得多。未调味的蔗糖水具有类似的效果。控制体重的新理论帮助发现了这种效果,它假设与卡路里相关的味道会增加人体脂肪的设定值:关联越强,增加的幅度就越大。在两餐之间,设定点下降。持续数月或数年的自我实验似乎是产生合理的新想法的好方法。

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